Skip to main content
OpenTrials

Clinical trial condition

Alpha 1-Antitrypsin Deficiency

Explore clinical trials studying Alpha 1-Antitrypsin Deficiency. Study availability and eligibility vary by location and protocol.

33 public trials 6 recruiting studies
Refine in advanced search Browse all conditions

Alpha 1-Antitrypsin Deficiency trial results

Completed

Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema

NCT05856331

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • University of Alabama at Birmingham- Site Number : 105 Birmingham, Alabama, United States
  • University of Alabama at Birmingham Birmingham, Alabama, United States
  • St Joseph's Hospital and Medical Center- Site Number : 126 Phoenix, Arizona, United States
  • St Joseph's Hospital and Medical Center Phoenix, Arizona, United States
View all 65 locations
View Trial Details
Completed

Study of DCR-A1AT in Healthy Adult Volunteers

NCT04174118

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Auckland Clinical Studies Grafton, Auckland, New Zealand
  • Clinical Trial Consultants AB Uppsala, Sweden
View Trial Details
Completed

A Phase 1, First-in-human Study of VX-634

NCT05579431

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Celerion - Tempe Tempe, Arizona, United States
  • University of Florida Gainesville, Florida, United States
  • Central Florida Pulmonary Group, P.A. Orlando, Florida, United States
  • ICON Lenexa Lenexa, Kansas, United States
View Trial Details
Completed

A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo.

NCT03636347

Conditions
Alpha 1-Antitrypsin Deficiency, COPD, Chronic Disease, +14 more
Locations
  • University of Alabama, Birmingham (UAB) Birmingham, Alabama, United States
  • UCLA Medical Center Los Angeles, California, United States
  • UC Davis Medical Centre Sacramento, California, United States
  • PMG Research of Wilmington Wilmington, North Carolina, United States
View all 26 locations
View Trial Details
Completed

Pharmacokinetic Study of ARALAST (Human Alpha1- PI)

NCT00242385

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Adelaide, South Australia, Australia
  • Woodville, South Australia, Australia
  • Fitzroy, Victoria, Australia
  • Nedlands, Western Australia, Australia
View Trial Details
Completed

Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor)

NCT00396006

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Adelaide, South Australia, Australia
  • Melbourne, Victoria, Australia
  • Nedlands, Western Australia, Australia
  • Otahuhu, Auckland, New Zealand
View Trial Details
Completed

Alpha-1 Foundation Research Registry

NCT00499941

Conditions
Alpha 1-Antitrypsin Deficiency, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Digestive System Diseases, +9 more
Locations
  • Medical University of South Carolina. Division of Pulmonary and Critical Care Medicine Charleston, South Carolina, United States
View Trial Details

Related conditions