Tooth Mousse and Fluoride in Dentin Hypersensitivity Treatment

GC Tooth Mousse, a complex containing amorphous calcium phosphate (ACP) and casein phosphopeptide (CPP), is recommended in dentin hypersensitivity reduction due to its ability to block opened dentinal tubules. It acts synergistically with fluorine in slowing caries progression. Whether CPP-ACP can act synergistically with fluorine in the dentin hypersensitivity treatment is unknown. The aim of this study was to assess the effect of CPP-ACP combined with fluoride varnish in cervical dentin hypersensitivity treatment.

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Key information

Conditions

Dentin Hypersensitivity Dentin Sensitivity Stomatognathic Diseases Tooth Diseases

Age range

26 year–66 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology

Wuhan, Hubei, 430030, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

subjects with a minimum of three cervical hypersensitive teeth at both sides of the dental arch

Exclusion criteria

dentin hypersensitivity caused by caries lesions
fracture of restoration
chipped teeth
marginal gaps
post-operative sensitivity
cracked-tooth syndrome, and which were confirmed by periapical radiographs and teeth with cervical fillings

Treatment and study plan

Primary outcomes

ANOVA

Time frame: June 2008

Secondary outcomes

T-test

Time frame: June 2008

Sponsors and collaborators

Lead sponsor

Huazhong University of Science and Technology

Other

Collaborators

National Natural Science Foundation of China

Registry information

Official study title

Combined Tooth Mousse and Fluoride Varnish in Dentin Hypersensitivity Treatment

Important dates

Study start: 2007
Primary completion: 2008
Study completion: 2008
First posted: Jun 23, 2009
Registry last updated: Jun 23, 2009

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed