University Hospital Ostrava
Ostrava, Moravian-Silesian Region, 70800, Czechia
NCT Number: NCT02587546
The purpose of the study is to compare results of the treatment of tumorous and non-tumorous laryngotracheal stenosis using thulium contact laser versus carbon dioxide laser used in the past.
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Notify Me18 year–70 year
All sexes
Interventional
Not applicable
Ostrava, Moravian-Silesian Region, 70800, Czechia
Laryngotracheal stenosis is a serious disease significantly worsening the quality of life. Impaired breathing often leads to tracheotomy, deterioration of the voice leads to communication problems with others and swallowing problems are often present, as well The main causes of laryngotracheal stenosis are post intubation and post tracheostomy conditions, inflammatory process (often autoimmune), tumors (mainly squamous cell carcinoma and chondroma) and trauma. Within the last years there is substantial shift in the treatment strategy from open surgery to endoscopic techniques. However, surgical treatment is often difficult due to demanding exposure of tumor and problematic margins control.
In recent years there has been a development of particular techniques of endoscopic resection of tumors and non-malignant laryngeal glottic and subglottic stenosis using a carbon dioxide (CO2) laser with promising improvement of treatment results.
However, CO2 laser has some limitations, particularly in the treatment of tumors spreading into anterior commissure, because CO2 laser beam cannot get "around the corner". Moreover, subglottic area is also difficult to be reached by CO2 laser beam. Therefore, contact laser with adjustable manipulators with possibility to bend tip of manipulator according to the actual need seems to be of some advantage.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
treatment of laryngeal carcinoma using thulium contact laser
treatment of bilateral vocal cord paralysis using thulium contact laser
treatment of subglottic stenosis using thulium contact laser
Time frame: 36 months
The percentage of carcinoma recurrence will be monitored and evaluated within the study subjects.
Time frame: 36 months
The percentage of decannulation will be monitored among the study subjects.
Time frame: 36 months
Voice quality will be assessed according to the Voice Handicap Index, which is an acknowledged measurement tool providing precise evaluation of the condition.
Time frame: 36 months
Swallowing will be assessed in the study group using the SWAL-QOL measurement tool (questionnaire) providing precise evaluation of the condition.
University Hospital Ostrava
Other
Thulium Contact Laser in the Treatment of Tumorous and Non-tumorous Laryngotracheal Stenosis
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