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OpenTrials
Completed

NCT Number: NCT01246830

The Use of 2D and 3D Imaging Modalities and Its Influence on Diagnosis and Treatment Planning in Orthodontics

Research questions:

1. Will the panoramic images derived from cone beam CT data give better diagnostic ability than conventional panoramic radiographs? 2. Will 3D cephalometric analysis offer the orthodontists and surgeons better information for treatment planning? 3. Will the 3D cephalometric analysis give more accurate treatment plan and better treatment outcome?

General hypothesis and special aims

Overall aims:

* To compare 2D versus 3D cephalometric analysis: treatment planning and therapeutic outcome. * To determine the accuracy and diagnostic ability and usability of the 3D cephalometric analysis. * To evaluate the diagnostic ability and usability of the panoramic image derived from cone beam CT data as compared to 2D panoramic images. * To evaluate the value of the cone beam CT data in cephalometric analysing process for orthodontic and maxillofacial surgery treatment.

Hypotheses:

1. The availability of the 3D cephalometric analysis influences the orthodontic and maxillofacial treatment plan and decision, and might change the treatment outcome. 2. Panoramic images derived from cone beam CT data may provide equal information for diagnosis as conventional panoramic images. 3. Cone beam CT will be able to replace "classic orthodontic imaging" being more time and dose efficient and having a beneficial effect on treatment outcome.

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Key information

Age range

12 year–25 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Katholieke Universiteit Leuven, Leuven, Belgium

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Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • age 12-25 years old
  • Patients with malocclusions
  • Patients with jaw relation defect both with or without the need of orthognathic surgery
  • Patients with maxillofacial defects: tumors and trauma
  • Patients with eruption problems: embedded or impacted teeth which have to be removed

Exclusion criteria

  • Patients with congenital deformities
  • Patients with systemic diseases that may effect the growth formation: growth factor defect and thyroid hormone defect.

Treatment and study plan

Panoramic radiograph, Cephalometric radiograph

Radiation

2D images that are used for orthodontic treatment planning

Cone-beam computed tomography (CBCT)

Radiation

CBCT data will be used in 3D cephalometric analysis softwares

Primary outcomes

  1. Cephalometric analysis

    Time frame: at treatment planning step and after 2 years of treatment

    linear and angular cephalometric measurement

Secondary outcomes

  1. outcome of orthodontic treatment

    Time frame: after 2 years of treatment

Sponsors and collaborators

Lead sponsor

Universitaire Ziekenhuizen KU Leuven

Other

Collaborators

  • KU Leuven

Registry information

Important dates

Study start
2012
Primary completion
2013
Study completion
2014
First posted
Nov 23, 2010
Registry last updated
Dec 3, 2014

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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