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NCT Number: NCT07008807

The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry

Facial asymmetry, the degree to which the two sides of the face differ in size, shape, or the arrangement of features, is a near-universal human characteristic. The intricate network of facial muscles plays a crucial role in both the static structure and the dynamic expressions of the face. The continuous pull and action of facial muscles can influence the development and positioning of underlying soft tissues and even, over extended periods, potentially impact skeletal structures.

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Key information

Conditions

Facial Asymmetry Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

16 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

orthodontic outpatient clinic, and students at Faculty of Dentistry, Alsalam University, Egypt

Tanta, Egypt

Location contact

Ayman Elmakakey, PhD

CONTACT

[email protected]

01006740689

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Presenting with noticeable facial asymmetry
  • Age > 16 years
  • General good health
  • Absence of specific neurological conditions affecting facial muscles.
  • Absence of congenital facial disorders that might cause facial asymmetry, like hemifacial microsomia and cleft lip and palate syndromes.

Exclusion criteria

  • History of facial trauma or surgery
  • Diagnosed Neuromuscular Disorders
  • Active facial infections.

Treatment and study plan

Primary outcomes

  1. Facial Electromyography (EMG)

    Time frame: Day 1

  2. Facial Asymmetry Measurement

    Time frame: Day 1

    assesses differences between the two sides of the face using various techniques, both two-dimensional (2D) and three-dimensional (3D)

Secondary outcomes

  1. Demographic and Clinical Data

    Time frame: Day 1

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed E. Ali, PhD

CONTACT

[email protected]

+201011212425

Nehad A. Abo-zaid, PhD

CONTACT

Sponsors and collaborators

Lead sponsor

South Valley University

Other

Registry information

Official study title

The Facial Muscular Activity: A Paradigm for Understanding Facial Asymmetry, A Prospective Correlation Study

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jun 6, 2025
Registry last updated
Jun 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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