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NCT Number: NCT07610200

Effects of Myofascial Release Therapy on Body Posture and Facial Symmetry

This randomized controlled study aims to investigate the effects of myofascial release therapy on body posture and facial symmetry in healthy individuals. Postural disorders and fascial tension may lead to biomechanical alterations not only in the musculoskeletal system but also in facial soft tissues and symmetry. Myofascial release techniques are widely used in physiotherapy to improve fascial mobility, reduce tissue tension, and support postural alignment. However, the potential effects of these interventions on facial symmetry have not been sufficiently investigated.

A total of 60 healthy participants will be included in the study and randomly assigned to either an intervention group or a control group. Participants in the intervention group will receive myofascial release therapy twice weekly for 6 weeks, while the control group will not receive any physical intervention during the same period. Body posture and facial symmetry assessments will be performed at baseline and after the intervention period.

Postural assessment will be conducted using the PostureScreen Mobile application through standardized anterior, posterior, and lateral photographs. Facial symmetry will be evaluated using anthropometric facial landmarks identified on standardized facial photographs. Directional asymmetry scores, linear measurements, proportional analyses, and angular measurements will be calculated.

The study is expected to provide evidence regarding the relationship between fascial interventions, postural alignment, and facial symmetry, and may contribute to the development of new physiotherapy approaches targeting fascial and postural dysfunctions.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

About this study

Body posture and fascial balance are closely associated with musculoskeletal health and biomechanical alignment. Impairments in postural alignment may contribute to abnormal loading patterns, muscular imbalance, fascial tension, and compensatory movement strategies throughout the body. Recent fascial theories suggest that fascial continuity may influence not only spinal and extremity alignment but also craniofacial structures and facial symmetry. Increased fascial tension, particularly in the cervical and thoracic regions, may alter soft tissue mechanics and contribute to asymmetrical facial appearance.

Myofascial release therapy is a manual therapy approach commonly used in physiotherapy to improve fascial mobility, decrease tissue restriction, reduce pain, and optimize postural alignment. Although previous studies have investigated the effects of myofascial interventions on musculoskeletal pain and posture, limited evidence exists regarding their influence on facial symmetry and facial anthropometric characteristics.

The present study is designed as a randomized controlled trial to evaluate the effects of myofascial release therapy on body posture and facial symmetry in healthy individuals. A total of 60 participants will be recruited and randomly allocated into intervention and control groups using a stratified randomization method based on dominant side characteristics. The intervention group will receive myofascial release therapy twice weekly for 6 weeks, whereas the control group will undergo only observation and assessment procedures during the same period.

The myofascial intervention protocol will include standardized manual therapy techniques targeting cervical, thoracic, shoulder, and fascial regions. The techniques will consist of single arm pull, lateral neck shoulder release, thoracic transverse plane technique, and anterior cervical fascial release applications performed by a trained physiotherapist.

Body posture assessment will be performed using the validated PostureScreen Mobile application. Standardized anterior, posterior, and lateral photographs will be analyzed to evaluate postural alignment parameters including forward head posture, shoulder asymmetry, spinal alignment, pelvic tilt, thoracic kyphosis, lumbar lordosis, and lower extremity alignment characteristics.

Facial symmetry assessment will be conducted using standardized digital facial photographs obtained under controlled environmental conditions. Anthropometric facial landmarks including exocanthion, endocanthion, alare, cheilion, zygion, and gonion points will be identified. Linear, proportional, and angular measurements will be calculated to determine facial asymmetry levels. Directional asymmetry scores will also be calculated to quantitatively evaluate right-left facial asymmetry.

Primary outcome measures will include changes in facial directional asymmetry scores and postural alignment parameters after the intervention period. Secondary analyses will investigate the relationship between postural characteristics, dominant side, physical activity habits, and facial symmetry variables.

The findings of this study may contribute to understanding the biomechanical relationship between fascial interventions, posture, and craniofacial symmetry. Additionally, the results may provide preliminary evidence for the use of fascial-based physiotherapy approaches in postural rehabilitation and facial asymmetry management.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy individuals aged between 18 and 45 years
  • Ability to understand and follow study instructions
  • Independent performance of daily living activities
  • No regular physiotherapy or manual therapy treatment within the previous 3 months
  • Willingness to participate voluntarily and sign the informed consent form
  • Ability to attend assessment and intervention sessions regularly

Exclusion criteria

  • History of neurological or orthopedic disorders affecting posture or facial symmetry
  • Current musculoskeletal injury or ongoing rehabilitation treatment
  • Previous facial, spinal, or major musculoskeletal surgery or trauma
  • Pregnancy
  • Use of medications affecting muscle tone or neuromuscular function
  • Psychiatric or cognitive disorders limiting study participation
  • Inability to comply with study procedures

Treatment and study plan

Myofascial release therapy

Procedure

Participants assigned to the intervention group will receive standardized myofascial release therapy performed by a trained physiotherapist twice weekly for 6 weeks. The intervention protocol will include single arm pull, lateral neck shoulder release, thoracic transverse plane technique, and anterior cervical fascial release techniques targeting cervical, thoracic, shoulder, and fascial regions. Each session will be conducted under standardized clinical conditions to improve fascial mobility, reduce tissue tension, and support postural alignment and facial symmetry.

Other names: Myofascial Therapy, Fascial Release Therapy, Manual Myofascial Release

Primary outcomes

  1. Change in Facial Directional Asymmetry Score

    Time frame: Baseline and after 6 weeks of intervention

    Facial symmetry will be evaluated using standardized digital facial photographs and anthropometric facial landmarks. Directional asymmetry scores will be calculated by comparing right and left facial measurements before and after the intervention period.

Study contacts

Contact information is provided by the study sponsor or research team.

Ece Acar, Assistant Professor, Physiothe

CONTACT

[email protected]

+905457925035

Eylül ESEN, MsC

CONTACT

[email protected]

+905385799415

Sponsors and collaborators

Lead sponsor

Ece ACAR

Other

Registry information

Official study title

Effects of Myofascial Release Therapy on Body Posture and Facial Symmetry in Healthy Individuals: A Randomized Controlled Trial

Acronym: MYOPOST-FACE

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
May 27, 2026
Registry last updated
May 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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