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OpenTrials
Completed

NCT Number: NCT03089437

The Effects of Prolonged Standing Compared to Prolonged Sitting on Postprandial Lipemia

The effects of 12 hours of prolonged standing will be compared to prolonged standing on a high fat tolerance test the following day. Plasma triglycerides, insulin, and glucose will be measured in a crossover study design.

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Key information

Conditions

Metabolic Syndrome Arterial Occlusive Diseases Arteriosclerosis Atherosclerosis Cardiovascular Diseases Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Nutritional and Metabolic Diseases Vascular Diseases

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Texas at Austin Human Performance Laboratory

Austin, Texas, 78712, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

-

Exclusion criteria

  • heart problems
  • coronary artery disease
  • hypertension
  • respiratory problems
  • musculoskeletal problems that prevent prolonged standing or sitting
  • obesity
  • susceptibility to fainting

Treatment and study plan

Prolonged Standing

Behavioral

Subject will stand for 12 hours and undergo a high fat tolerance test the subsequent day

Prolonged sitting

Behavioral

Subject will sit for 12 hours and undergo a high fat tolerance test the subsequent day

Primary outcomes

  1. Plasma Triglycerides

    Time frame: 6 hours

    The area under the curve for plasma triglycerides from hourly samples during a 6 hour high fat tolerance test

  2. Plasma Insulin

    Time frame: 6 hours

    The area under the curve for plasma insulin from hourly samples during a 6 hour high fat tolerance test

  3. Plasma Glucose

    Time frame: 6 hours

    The area under the curve for plasma glucose from hourly samples during a 6 hour high fat tolerance test

Sponsors and collaborators

Lead sponsor

University of Texas at Austin

Other

Registry information

Important dates

Study start
2017
Primary completion
2017
Study completion
2018
First posted
Mar 24, 2017
Registry last updated
Oct 4, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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