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Completed

NCT Number: NCT03352063

Prolonged Sitting on Responses to Short-Term Exercise Training

Prolonged sitting has been shown to effect the response to a high fat tolerance test (HFTT) after acute exercise. This study will evaluate the effect of prolonged sitting on response to a HFTT after a short term training period.

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Key information

Conditions

Atherosclerosis Arterial Occlusive Diseases Arteriosclerosis Cardiovascular Diseases Glucose Metabolism Disorders Hyperinsulinism Insulin Resistance Metabolic Diseases Metabolic Syndrome Nutritional and Metabolic Diseases Vascular Diseases

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Texas at Austin Human Performance Laboratory

Austin, Texas, 78712, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 to 35 years

Exclusion criteria

  • cardiovascular problems (e.g. pre-existing heart issues, coronary artery disease, hypertension, etc.)
  • respiratory problems
  • musculoskeletal problems that prevent prolonged sitting or exercise
  • obesity
  • susceptibility to fainting
  • pregnancy

Treatment and study plan

Prolonged sitting with exercise

Behavioral

Subjects will commit to sitting more than 11 hours per day and taking less than 5000 steps per day while participating in exercise training.

Active walking with exercise.

Behavioral

Subjects will commit to sitting less than 5 hours per day and taking more than 10000 steps per day while participating in exercise training.

Primary outcomes

  1. Plasma Triglycerides

    Time frame: 6 hours

    Areas under the curve for triglyceride concentration will be calculated for hourly samples from a 6-hour lipid tolerance test

Secondary outcomes

  1. Plasma Insulin

    Time frame: 6 hours

    Areas under the curve for insulin concentration will be calculated for hourly samples from a 6-hour lipid tolerance test

  2. Plasma glucose

    Time frame: 6 hours

    Areas under the curve for glucose concentration will be calculated for hourly samples from a 6-hour lipid tolerance test

Sponsors and collaborators

Lead sponsor

University of Texas at Austin

Other

Registry information

Official study title

Effect of Prolonged Sitting on Metabolic and Cardiovascular Responses to Short-Term Exercise Training

Important dates

Study start
2018
Primary completion
2020
Study completion
2020
First posted
Nov 24, 2017
Registry last updated
Sep 30, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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