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OpenTrials
Completed

NCT Number: NCT03032939

The Effect of Tracheal Intubation on AC and DC Components of a Photoplethysmograph

Intraoperative stress responses (vasoconstriction and changes in heart rate) and postoperative pain can be monitored using photoplethysmography (PPG). PPG measures changes in tissue volume noninvasively. Therefore it can measure acute changes in arterial diameter (vasoconstriction). PPG signal has two components, AC and DC. Effects of noxious stimuli-induced stress responses (vasoconstriction) have not been studied on the DC component of PPG. The aim of this study was to investigate the effect of a known noxious stimulus (endotracheal intubation) on both the AC and DC components of PPG.

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Key information

Conditions

Anesthesia Intubation Complication

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Elective surgery
  • General endotracheal anesthesia
  • Over 18 years of age
  • Healthy

Exclusion criteria

  • Vascular disease
  • Liver or kidney disease
  • Overweight

Treatment and study plan

Endotracheal Intubation

Procedure

standard endotracheal intubation of surgical patients after induction of anesthesia

Primary outcomes

  1. Photoplethysmography

    Time frame: within 60 seconds of intubation

    changes in AC and DC components of photoplethysmography

Secondary outcomes

  1. Pulse rate

    Time frame: within 60 seconds of intubation

    Pulse rate from photoplethysmograph

Sponsors and collaborators

Lead sponsor

University of California, San Francisco

Other

Registry information

Official study title

The Effect of Tracheal Intubation Induced Autonomic Response on Photoplethysmography

Important dates

Study start
2007
Primary completion
2012
Study completion
2015
First posted
Jan 26, 2017
Registry last updated
Jan 26, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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