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Completed

NCT Number: NCT00668980

Symbolic Representation in Young Children With Down Syndrome

The aim of this study is to characterize the process of constitution of symbolic representation in infants with Down syndrome, as well as to investigate the relationship between gestures and the emergence of oral language. The investigators hypothesis is that children with Down syndrome could present difficulties during the constitution of symbolic representation that may be related to later deficits on expressive language, generally observed in these children.

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Key information

Conditions

Down Syndrome Abnormalities, Multiple Behavior Chromosome Disorders Communication Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Gestures Intellectual Disability Kinesics Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations Nonverbal Communication

Sex eligibility

All sexes

Study type

Observational

Primary location

APAE Sao José dos Campos, São José dos Campos, São Paulo, Brazil

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About this study

According to the Genetic Epistemology, language development is directly related to cognitive construction. Such relationship is clearly observed after the constitution of representation that allows one individual to express his or her thinking through language.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

for Study Group:

  • genetic diagnosis of Down Syndrome
  • be at the 4th stage of sensorimotor period at the initial assessment
  • good health conditions
  • good results on audiologic evaluation
  • pediatric and ear, nose and throat periodic check ups.

Inclusion criteria

for Control Group:

  • good health conditions
  • be at the 4th stage of sensorimotor period at the initial assessment
  • pediatric and ear, nose and throat periodic check ups.

Exclusion criteria

for all groups:

  • submission to long term hospitalizations due to heart diseases and major respiratory airway infections, that may interfere in the child's global development
  • presence of visual or auditory important deficits
  • historic of prematurely and/or low birth weight

Treatment and study plan

Primary outcomes

  1. Performance on monthly assessments administered after the initial evaluation

    Time frame: 12 months

Sponsors and collaborators

Lead sponsor

University of Sao Paulo

Other

Collaborators

  • Fundação de Amparo à Pesquisa do Estado de São Paulo

Registry information

Official study title

The Constitution of Symbolic Representation in Young Children With Down Syndrome

Important dates

Study start
2006
Primary completion
2009
Study completion
2009
First posted
Apr 29, 2008
Registry last updated
Jan 14, 2010

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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