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Completed

NCT Number: NCT05472701

SWAP-MEAT Athlete: Three Diets on Athletic Performance

This study aims to investigate the impact of two plant-based diets-whole food plant-based (WFPB) and plant-based meat alternatives (PBMA)-vs. an omnivorous diet (Animal) on endurance and muscular strength in recreational athletes.

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Key information

Age range

18 year–35 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Stanford University

Stanford, California, 94305, United States

About this study

Plant-based diets are environmentally sustainable and beneficial for cardiovascular health, but athletes are often concerned that these diets do not contain enough protein to support athletic performance. However, few randomized trials investigating the effect of plant-based vs. omnivorous diets on athletic performance have been conducted. Within this randomized crossover trial, recreational runners and resistance trainers will be assigned to three diets for four weeks each (WFPB, PBMA, and Animal). PMBA is an emerging, modern type of plant-based diet for which the impact on athletic performance has not yet been assessed. Participants will complete athletic fields at baseline and after each diet, and athletic performance on diets and study feasibility in this cohort of recreational athletes will be assessed. The study design was inspired by the original SWAP-MEAT study that investigated cardiovascular risk factors in adults consuming 8-week omnivorous and plant-based meat alternative diets (Crimarco, 2020).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Generally healthy omnivorous adults between 18 and 35 years of age who report typically consuming at least 1 serving of meat per day and are willing to consume ~2 servings per day of animal meat, plant-based meat alternatives, and whole-food plant proteins.
  • Participants will have been consistent recreational runners or weightlifters (3-4 times per week) for at least the prior 1 year, and currently run or lift 3-4 times per week.
  • Runners will engage in at least 150 minutes of moderate-to-vigorous aerobic activity or 75 minutes of vigorous activity per week. All participants will have habitually consumed an omnivorous diet for at least months.
  • Participants will have self-reported good health and BMI 18.5-30.0.
  • Participants must be able to commit to running or resistance training at least 3-4 times per week for the 12 week duration of the study.

Exclusion criteria

  • Individuals who have participated in any restrictive diet within the last month, have any known nutrient intolerances, have orthopedic limitations, are participating in any other physical activity or diet study;
  • Individuals consuming any performance enhancing drugs or medications known to interfere with athletic performance;
  • Individuals who have a chronic disease or eating disorder, are currently pregnant or intend to become pregnant in the next three months, or have an intent to compete in any physical activity competition within the next 3 months.

Treatment and study plan

Diet order: WFPB, PBMA, Animal

Behavioral

Participants followed the WFPB, PBMA, and Animal diets (in this order) for 4 weeks each.

WFPB, Animal, PBMA

Behavioral

Participants followed the WFPB, Animal, and PBMA diets (in this order) for 4 weeks each.

PBMA, WFPB, Animal

Behavioral

Participants followed the PBMA, WFPB, and Animal diets (in this order) for 4 weeks each.

PBMA, Animal, WFPB

Behavioral

Participants followed the PBMA, Animal, and WFPB diets (in this order) for 4 weeks each.

Animal, WFPB, PBMA

Behavioral

Participants followed the Animal, WFPB, and PBMA diets (in this order) for 4 weeks each.

Animal, PBMA, WFPB

Behavioral

Participants followed the Animal, PBMA, and WFPB diets (in this order) for 4 weeks each.

Primary outcomes

  1. Cooper 12-Minute Timed Run Test (Runners)

    Time frame: Baseline, Week 4, Week 8, Week 12

    Change from baseline in distance covered on a 12-minute timed run after each diet phase

  2. Composite Machine Strength Index (Resistance Trainers)

    Time frame: Baseline, Week 4, Week 8, Week 12

    Change from baseline in composite machine strength index (sum of 3-rep max chest press, leg press, and lat pull-down) after each diet phase

Secondary outcomes

  1. Estimated VO2 max (Runners)

    Time frame: Baseline, Week 4, Week 8, Week 12

    Change in VO2 max, estimated from training data compiled by Garmin Forerunner 235 after each diet phase

  2. Maximum push-up and pull-up test

    Time frame: Baseline, Week 4, Week 8, Week 12

    Change from baseline in maximum number of repetitions completed of push-up and pull-ups prior to exhaustion after each diet phase

  3. Dietary intake and adherence

    Time frame: Baseline, Week 4, Week 8, Week 12

    a. Nutrient composition of each diet and adherence to diet in servings of protein source consumed per week, via weekly dietary logs

  4. Diet satisfaction

    Time frame: Week 4, Week 8, Week 12

    Score on Food Acceptability Questionnaire, measuring taste, appeal, and overall diet satisfaction, after each diet. We used the "Food Acceptability Questionnaire", with a minimum value of 1 and a maximum value of 7. A higher score indicates better food acceptability.

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Registry information

Official study title

SWAP-MEAT (Study With Appetizing Plant-Food, Meat Eating Alternatives Trial) Athlete

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
Jul 25, 2022
Registry last updated
Feb 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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