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Completed

NCT Number: NCT05760001

The IGNITE for Kids Study on Concentrated Investment in Black Neighborhoods and Child Health and Well-Being

Black children and adults in the United States fare worse across nearly every health indicator compared to White individuals. In Philadelphia, the location of this study, these health disparities result in a stark longevity gap, with average life expectancies in poor, predominantly Black neighborhoods being 20 years lower than in nearby affluent, predominantly White neighborhoods. The investigators will conduct a cluster randomized controlled trial (RCT) of a suite of place- based and financial-wellbeing interventions at the community, organization, and individual/household levels that address the social determinants of racial health disparities. At the community level, the investigators address underinvestment in Black neighborhoods by implementing vacant lot greening, abandoned house remediation, tree planting, and trash cleanup. At the organization level, the investigators partner with community-based financial empowerment providers to develop cross-organizational infrastructure to increase reach and maximize efficiency. At the individual/household levels, the investigators increase access to public benefits, financial counseling and tax preparation services, and emergency cash assistance. The investigators will test this "big push" intervention in 60 Black neighborhood micro-clusters, with a total of 480 children. The investigators hypothesize that this "big push" intervention will have significant impact on children's health and wellbeing.

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Key information

Age range

3 year–19 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

About this study

Black individuals in the United States fare worse than White individuals across almost every social, economic, and health indicator. The Black health disadvantage starts at birth, reflecting the cumulative toll of racialized social stressors and healthcare discrimination on maternal health and resulting in higher rates of pre-term birth and low birth weight. Black youth are disproportionately exposed to environmental toxins such as lead and adverse childhood events such as financial hardship and neighborhood violence. Black children also have higher rates of chronic disease, including asthma and diabetes. These and other forces result in inequities in child health and well-being and can also impact children's educational and earning potential. Furthermore, these inequities culminate in a stark racial longevity gap: in Philadelphia, the location of this study, life expectancy for people living in a poor, predominantly Black neighborhood is 20 years lower than for people living in a nearby affluent, predominantly White neighborhood.

The fundamental cause of these striking and pervasive disparities is structural racism - the confluence of deep historical, institutional, cultural, and ideological forces that unequally distribute resources and risks across racialized groups. Structural racism patterns health by affecting a range of interconnected, mutually reinforcing social determinants of health at the national, neighborhood, household, and individual levels. Most notably, longstanding, systematic disinvestment has resulted in highly segregated Black neighborhoods with dilapidated environmental conditions and severe economic insecurity within Black households, leading to a "feedback loop of concentrated racial disadvantage," all of which have been strongly tied to poor health.

Most interventions seeking to address racial health disparities focus on individual-level behaviors and outcomes, or individual channels by which structural racism harms health. However, by failing to address upstream social determinants, these interventions have had limited population level impact. A multi-level, multi-component intervention package focused on a range of social determinants of health is necessary to meaningfully address structural racism as a fundamental cause of racial health disparities. In this trial, we aim to implement such a multi-level, multi-component intervention and then evaluate its impact on child health and well-being.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Child is between the ages of 3 and 17 years at the start of the trial (between the ages of 5 and 19 years at the end of the trial)
  • Parent/caregiver is at least 18 years of age
  • Parent/caregiver has the ability to communicate via text messaging
  • Parent/caregiver is comfortable communicating in English
  • Child is a permanent resident of the home where they are to be enrolled
  • Parent/caregiver has knowledge of their household finances

Exclusion criteria

  • Children who plan to move out of the study microcluster within 6 months
  • Children whose caregivers are unable to fully consent and participate based on CC team assessment

Treatment and study plan

Assigned Interventions

Other

Financial well-being interventions:

  • Tax preparation; access to public benefits; financial counseling and microgrants

Place-based interventions:

  • Vacant lot greening; abandoned house remediation; trash cleanup; tree planting

Primary outcomes

  1. Child Health Questionnaire Parent Form 28 (CHQ-PF28) Composite Score

    Time frame: 24 months

    Composite index using CHQ-28 scoring method, based on a series of 28 questions focused on overall child health, activity limitation, emotional/behavioral difficulties, mood, relationships, and family cohesion. (Child Health Questionnaire)

Secondary outcomes

  1. Parent-reported child health

    Time frame: 24 months

    (5-pt Likert ranging from poor to excellent) (Child Health Questionnaire)

  2. Caregiver-reported child health care utilization, well child visits

    Time frame: 24 months

    Well child visits in previous 12 months (National Survey of Children's Health)

  3. Caregiver-reported child health care utilization, sick clinic visits

    Time frame: 24 months

    Sick clinic visits in previous 12 months (National Survey of Children's Health)

  4. Caregiver-reported child health care utilization, emergency room visits

    Time frame: 24 months

    Emergency room visits in previous 12 months (National Survey of Children's Health)

  5. Caregiver-reported child health care utilization, hospitalization

    Time frame: 24 months

    Hospitalizations in previous 12 months (National Survey of Children's Health)

  6. Forgone health care

    Time frame: 24 months

    Caregiver report of whether the child needed but did not receive medical, mental health, dental, or vision care in the previous 12 months (National Survey of Children's Health)

  7. Uninsurance or gaps in insurance

    Time frame: 24 months

    Uninsurance or gaps in insurance in the previous 12 months (National Survey of Children's Health)

  8. School attendance

    Time frame: 24 months

    School attendance, based on Philadelphia school district data (Proportion of school days attended, internally developed)

  9. School performance

    Time frame: 24 months

    School performance, based on Philadelphia school district data (Grade point average over previous 12 months, internally developed)

  10. Rate of preterm birth

    Time frame: 24 months

    Rate of preterm birth (birth < 37 weeks of gestation age), based on Pennsylvania birth certificate data

  11. Rate of low birthweight

    Time frame: 24 months

    Rate of low birthweight (birthweight <2000 grams), based on Pennsylvania birth certificate data

  12. Health care utilization: emergency room visits in the previous 12mon

    Time frame: 24 months

    Monthly or quarterly data from 2 years prior to enrollment through approximately 1 year after from HealthShare Exchange

  13. Health care utilization: hospitalizations

    Time frame: 24 months

    Health care utilization: hospitalizations in the previous 12 months, based on Children's Hospital of Philadelphia EHR data

Sponsors and collaborators

Lead sponsor

University of Pennsylvania

Other

Collaborators

  • Children's Hospital of Philadelphia

Registry information

Official study title

A Randomized Controlled Trial of Concentrated Investment in Black Neighborhoods to Address Structural Racism as a Fundamental Cause of Poor Child Health

Important dates

Study start
2023
Primary completion
2026
Study completion
2026
First posted
Mar 8, 2023
Registry last updated
Jul 30, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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