MIT Media Lab
Cambridge, Massachusetts, 02139, United States
Location status: Recruiting
NCT Number: NCT07652437
Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA. Pain, activity limitations and disability are common symptoms. Exercise is widely recommended as a non-invasive, first line strategy for people with knee OA. Yet, less than 1/3 of adults with knee OA meet recommended levels of physical activity, and rates are even lower among people who are overweight. Furthermore, adherence to evidence-based structured programs is poor once the therapeutic support is removed. End stage disease is treated by total joint replacement. Under-active people with knee OA would benefit from general walking activity, even if joint replacement surgery is expected; however, walking is difficult and motivation is low. Thus, people with knee OA encounter a difficult paradox: exercise could help decrease pain and improve function but doing so can be difficult and may not always be possible. There is a tremendous need to address this situation. This is a small device-feasibility study evaluating the Dephy ExoBoot, a wearable powered exoskeleton, in individuals with knee OA. The study assesses whether the device can reliably deliver positive assistance during walking and is tolerated across walking tasks. Additional measures, including changes in knee loading and walking speed with versus without the device, are also collected.
Interested in participating?
Request Info21 year–100 year
All sexes
Interventional
Not applicable
Cambridge, Massachusetts, 02139, United States
Location status: Recruiting
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Individuals administered the wearable intervention will have the device accurately predict appropriate dynamics based on non-invasive sensor inputs, adapt assistance timing and magnitude to match individual gait patterns, demonstrate reliable performance across various walking conditions and provide assistance that integrates naturally with the user's biomechanics
Time frame: Up to 4 sessions across 4 weeks, each lasting up to 2 days.
Number of participants that complete the walking protocol with device providing assistance without device-related restrictions.
Time frame: Up to 4 sessions across 4 weeks, each lasting up to 2 days.
Quantitative analysis of knee adduction moment (N*m / kg) between device and no device condition.
Time frame: Up to 4 sessions across 4 weeks, each lasting up to 2 days.
Analysis of walking speed (m/s) changes between device and no device conditions
Contact information is provided by the study sponsor or research team.
Massachusetts Institute of Technology
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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