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Completed

NCT Number: NCT04379206

Social Network Approach for Increasing Testing Coverage Among Men Who Have Sex With Men

HIV testing is essential in shortening the time to identify a new infection, the first 90 of the UNAIDS 90-90-90 targets. However, over one-third of the men who have sex with men (MSM) had never been tested for HIV; even if they did, one-fifth had their tests done more than a year ago. Assortative mixing pattern observed in the HIV-positive MSM group shaped the transmission dynamics and could be leveraged for intervention. Barriers to access HIV testing services could, on the other hand, be hurdled by self-tests. A network approach for intervention could therefore be promising in delivering effective HIV self-tests. To experiment with such an approach, a 2-phase study was conceptualised incorporating actual network-based referred HIV self-tests and an agent-based simulation evaluating its impact. Sixty-four MSM would be recruited as seeds for promoting HIV self-tests within their network and those being referred could refer their friends for the same after passing online training. To facilitate the process, an online platform would be developed offering information, collecting informed consent, requesting HIV self-test kits, returning results, performing online training, and referring peers. Participants could opt to receive self-tests by delivery or to conduct it on-site with staff assistance. A hotline with video conferencing support would be maintained to assist those who self-test at home. They could also choose between blood and oral fluid tests. Two user interfaces, namely gamification and neumorphism, would be randomly assigned. Primary outcomes to measure are number and proportion of MSM who had never or not tested within 12 months and the associating factors, and usability of the two user interfaces. Data collected in the empirical study would be used for parameterising the agent-based simulation to evaluate the impact of the approach in increasing testing coverage and shortening time to diagnosis. Its economic assessment would also be performed to cost each new infection to be identified. The approach could be feasible and effective to be adopted for future broader implementation for peer-led HIV self-test kit or HIV prevention message distribution.

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Key information

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • male
  • had sex with another male in the preceding year
  • able to communicate in written Chinese or English
  • normally resided in Hong Kong

Exclusion criteria

  • prisoners
  • having mental illnesses that informed consent cannot be obtained

Treatment and study plan

HIV self-test kit

Diagnostic Test

fingerprick and oral fluid HIV self-tests with optional on-site or hotline staff assistance

Graphical User Interface

Other

Gamification or neumorphism user interface

Primary outcomes

  1. effectiveness of the approach in reaching MSM who have never or not recently tested for HIV

    Time frame: Through study completion, at year 2

    proportion of testers who have never or not recently tested for HIV

  2. Usability and acceptability of two user interfaces

    Time frame: Through study completion, at year 2

    System Usability Scores (SUS) and proportion of testers giving a score of at least 71

Secondary outcomes

  1. Determinants of key actors in the social network

    Time frame: Through study completion, at year 2

    Network metrics predicting important actors in the referral network

  2. Preference of two forms of HIV self-testing

    Time frame: Through study completion, at year 2

    Proportion of testers favouring each form of self-testing

  3. Effect of network-based HIV self-test promotion in controlling transmission among MSM

    Time frame: Through study completion, at year 2

    Number of infections identified from the agent-based model

  4. Proportion and characteristics of promoters

    Time frame: Through study completion, at year 2

    Promoters are testers giving an SUS score of at least 80

Sponsors and collaborators

Lead sponsor

Chinese University of Hong Kong

Other

Registry information

Important dates

Study start
2021
Primary completion
2021
Study completion
2021
First posted
May 7, 2020
Registry last updated
Jan 11, 2022

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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