Serratus Posterior Plane Block vs Erector Spine Plane Block

Analgesia related to the administration of local anesthetic solution into the fascia of erector spinae muscle is mediated by the effect of local anesthetic on the posterior and lateral branches of the anterior part of the spinal nerve. Comparable analgesic efficiency after the administration of both nerve blocks would reject the widespread theory of the paravertebral site of effect of the local anesthetic in ESPB.

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Key information

Conditions

Regional Anesthesia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Krajská zdravotní, a.s. - Masarykova nemocnice v Ústí nad Labem, o.z.

Ústí nad Labem, Ústí nad Labem Region, 40011, Czechia

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patiens undergoing VATS-surgery

Exclusion criteria

Age < 20 years
Body Mass Index >35 kg/m2
Technical difficulties with the nerve block administration and/or subsequent bolus application
Abnormal course of the surgery (e.g. conversion to thoracotomy) or the postoperative phase (e.g. surgical revision of the chest)
Patient's refusal

Treatment and study plan

new type of peripheral block Serratus Posterior Plane Block

Procedure

Intervention will be Serratus Posterior Plane Block.

Primary outcomes

Cumulative opioid dose in 72 hours

Time frame: from end of surgery to 72 hours after the end surgery

Irrespective of the type of the block, 20 mls of 0.25 % bupivacaine will be administered to the block catether every 8 hours. Every patients will receive non-opioid analgesics according to standardized ward guideline. VAS score is recorded at least every 3 hours (except for time patient is asleep). Any time patient reports VAS score >=5, he/she will receive 5 mg of morphine intravenously (or equivalent dose of Oxycodone per os). Cumulative dose of opioids will be recorded.

Study contacts

Contact information is provided by the study sponsor or research team.

Daniel Nalos

CONTACT

[email protected]

+420737230792

Ondrej Maly

CONTACT

[email protected]

+420774145512

Sponsors and collaborators

Lead sponsor

Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s.

Other

Registry information

Official study title

Continuous Serratus Posterior Plane Block Versus Continuous Erector Spine Plane Block for Video-assisted Thoracoscopic Surgery: a Prospective Randomized Non-inferiority Trial

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2026
First posted: Jun 13, 2025
Registry last updated: Jun 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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