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OpenTrials
Completed

NCT Number: NCT02022189

Review of Kidney Biopsies of Dent Disease Patients

This study is being done to obtain pathology reports from all patients in the Dent disease registry who have had a kidney biopsy. The investigator will collect the biopsy slides and reports in an attempt to determine if they have any common findings.

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Key information

Conditions

Dent Disease Congenital, Hereditary, and Neonatal Diseases and Abnormalities Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genetic Diseases, Inborn Genetic Diseases, X-Linked Kidney Diseases Male Urogenital Diseases Renal Tubular Transport, Inborn Errors Urogenital Diseases Urologic Diseases

Sex eligibility

Male

Study type

Observational

Primary location

Mayo Clinic

Rochester, Minnesota, 55905, United States

About this study

If the patient agrees to be in the study, the patient will be asked to participate in the following:

  • Sign a consent form indicating the patient's willingness to participate.
  • Provide a signed medical release form allowing the investigator to request your official kidney biopsy reports, and also allowing the investigator to request the original slides for review. At the end of the study, all slides will be returned to the referring facility.
  • The investigator will also review your medical record

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • All patients in the Dent Disease Registry with a previous renal biopsy.

Exclusion criteria

  • None.

Treatment and study plan

Renal Biopsy

Procedure

Other names: All patients in the Dent Disease Registry with a previous renal biopsy.

Primary outcomes

  1. Biopsy changes

    Time frame: 2 years

    The primary outcome will be to determine the number of glomeruli, percent globally sclerotic glomeruli, percent focally sclerotic glomeruli, and the severity of interstitial fibrosis (none, mild, moderate, severe) and interstitial crystals (none, mild, moderate, severe)

Sponsors and collaborators

Lead sponsor

Mayo Clinic

Other

Registry information

Official study title

Systematic Review of Clinical Biopsies of Dent Disease Patients

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Dec 27, 2013
Registry last updated
Sep 22, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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