Preoperative Nutritional Status and Postoperative Acute Kidney Injury

There is a high prevalence of postoperative acute kidney injury (AKI) in patients who undergo intra-abdominal surgery, and it is particularly common in the elderly. Identifying high-risk patients for postoperative AKI early can facilitate the development of preventive and therapeutic management strategies.

The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients undergoing major abdominal surgery.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Acute Kidney Injury

Age range

65 year–100 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Rao Sun

Wuhan, China

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

aged ≥ 65 years
intra-abdominal procedures including gastric, colorectal, pancreatic, prostate, and urinary bladder surgeries, as well as abdominal exploration.
surgery duration lasting longer than 2 hours.

Exclusion criteria

patients with an American Society of Anesthesiologists (ASA) physical status V.
those with concurrent cardiac or renal surgeries.
those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis).
those did not have sufficient data required for nutritional evaluation or AKI evaluation.

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

Postoperative acute kidney injury

Time frame: Within 7 days after surgery

In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

Sponsors and collaborators

Lead sponsor

Rao Sun

Other

Registry information

Official study title

Prognostic Significance of Preoperative Nutritional Status for Postoperative Acute Kidney Injury in Elderly Patients Undergoing Major Abdominal Surgery

Important dates

Study start: 2023
Primary completion: 2023
Study completion: 2023
First posted: Jul 14, 2023
Registry last updated: Oct 6, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed