Skip to main content
OpenTrials
Completed

NCT Number: NCT06462755

Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population.

The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation.

Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

Completed

Looking for future studies?

Notify Me

Key information

Conditions

Postoperative Acute Kidney Injury

Age range

65 year–120 year

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries

Exclusion criteria

  • (1) Patients who underwent endoscopic or transplant procedures;
  • (2) Patients who underwent surgeries lasting longer than 10 hours;
  • (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) < 15 ml/min per 1.73 m2;
  • (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Number of participants with postoperative acute kidney injury

    Time frame: within seven days following surgery

    Postoperative acute kidney injury

Sponsors and collaborators

Lead sponsor

Chinese PLA General Hospital

Other

Registry information

Important dates

Study start
2009
Primary completion
2018
Study completion
2018
First posted
Jun 17, 2024
Registry last updated
Jul 8, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.