Skip to main content
OpenTrials
Recruiting

NCT Number: NCT06857630

Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery

Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of blood transfusion or various interventions to increase hemoglobin levels on outcomes continue to be debated. The effects of hemoglobin levels in emergency surgery patients on the development of postoperative AKI have been investigated in a small number of studies in the literature, and clear results have not yet been reported. This study was designed to evaluate the effect of hemoglobin levels on the development of AKI after adjustment for known predictive factors.

Recruiting

Interested in participating?

Request Info

Key information

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Özgür Kömürcü

Samsun, 55200, Turkey (Türkiye)

Location status: Recruiting

Location contact

özgür kömürcü, 1

CONTACT

[email protected]

90 505 5273180

About this study

Acute kidney injury (AKI) is a common complication in patients undergoing major surgery and is associated with both short-term morbidity and mortality and long-term adverse outcomes including the development of Chronic Kidney Failure. Optimization of hemoglobin levels for organ perfusion is essential, especially in critically ill patients. Although anemia is associated with severe organ failure, especially in coronary artery disease, the effects of various interventions such as blood transfusion or increasing hemoglobin levels on outcomes continue to be debated. This prospective observational study was planned to evaluate the effect of hemoglobin levels before emergency surgery on the development of postoperative AKI.

Emergency operated patients will be divided into two groups as Group AKI and Group non-AKI according to the development of postoperative renal failure. Postoperative AKI diagnosis and severity will be evaluated according to serum creatinine and/or urine output according to KDIGO (Kidney Disease: Improving Global Outcomes criteria).

Demographic characteristics of the patients, preoperative complete blood count, blood biochemistry characteristics, hemodynamic variables, fluid replacement, blood and blood product replacements, surgical characteristics, development and severity of AKI in the postoperative period will be recorded and the effect of hemoglobin level on the development of AKI will be evaluated.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing emergency non-cardiac surgery

Exclusion criteria

  • Known renal failure
  • Need for reoperation within 48 hours postoperatively
  • Exit status within 48 hours postoperatively
  • Known hematological disease
  • Known kidney transplantation
  • Urgent surgery planned due to urinary system related diseases
  • Patients who did not accept to participate in the study

Treatment and study plan

Observational

Other

Postoperative acute kidney injury and hemoglobin level relationship observation

Primary outcomes

  1. Acute renal failure.

    Time frame: 72 hours

    The effect of hemoglobin level before emergency surgery on the development of postoperative acute renal failure.

Secondary outcomes

  1. Hospital days

    Time frame: 1 month

    The effect of hemoglobin level before emergency surgery on the hospital days

Study contacts

Contact information is provided by the study sponsor or research team.

özgür kömürcü, 1

CONTACT

[email protected]

90 5055273180

özgür kömürcü, 2

CONTACT

[email protected]

90 505 5273180

Sponsors and collaborators

Lead sponsor

Samsun University

Other

Registry information

Official study title

The Association Between Preoperative Hemoglobin and Acute Kidney Injury in Emergency Surgery: A Prospective Observational Study

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Mar 4, 2025
Registry last updated
Mar 17, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.