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NCT Number: NCT07016685

Prognosis of Veno-Venous Extracorporeal Membrane Oxygenation in Emergency Thoracic Surgery

Veno-vneous extracorporeal membrane oxygenation (VV-ECMO) is an established support strategy for acute respiratory failure, but its role in the perioperative management of emergency thoracic surgery remains poorly defined. This retrospective, multicenter, observational study aims to assess the clinical outcomes and prognostic factors in this high-risk population. Patients undergoing emergency thoracic procedures requiring VV-ECMO will be compared to a control cohort of patients treated with VV-ECMO for medical respiratory failure. Data will be collected from two French academic centers (CHU Amiens-Picardie and CHU Dijon).

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Key information

Conditions

VV-ECMO ARDS ECMO Outcomes Emergency Surgery Mortality Propensity Score Matching Retrospective Cohort Thoracic Surgery

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

CHRU Amiens

Amiens, 80480, France

Location status: Recruiting

Location contact

Christophe Beyls, MD

CONTACT

[email protected]

33+3 22 08 78 66

Pierre Grégoire Guinot, MD

PRINCIPAL_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults ≥ 18 years
  • VV-ECMO initiated during or after emergency thoracic surgery
  • No opposition to data use

Exclusion criteria

  • Pregnant women
  • Veno-Arterial ECMO patients
  • Patients under legal protection

Treatment and study plan

Primary outcomes

  1. 90-day all-cause mortality

    Time frame: 90 days

Secondary outcomes

  1. 90-day mortality in oncologic vs. non-oncologic thoracic surgery

    Time frame: 90 days

  2. Postoperative complication rates

    Time frame: 90 days

    Postoperative complication rates (hemorrhagic, thrombotic, infectious)

Study contacts

Contact information is provided by the study sponsor or research team.

Christophe Beyls, MD

CONTACT

[email protected]

33+3 22 08 78

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire, Amiens

Other

Collaborators

  • Centre Hospitalier Universitaire Dijon

Registry information

Official study title

Prognostic Factors for 90-day Mortality in Patients Undergoing Veno-venous Extracorporeal Membrane Oxygenation for Emergency Thoracic Surgery

Acronym: PECUR

Important dates

Study start
2025
Primary completion
2025
Study completion
2026
First posted
Jun 12, 2025
Registry last updated
Jun 13, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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