University of Leeds, Leeds Dental Institute (DenTCRU)
Leeds, West Yorkshire, LS2 9LU, United Kingdom
NCT Number: NCT01622920
The investigators have now established a technique to measure enamel thickness which has been shown to work well in-vitro. The teeth tested so far, obtained from the Dental School Tissue Bank, have been molars or pre-molars. In these cases, the measurement is made more difficult by the curvature of the tooth surface and it seems likely that flatter larger, incisors would give more satisfactory results. The investigators therefore wish to establish in-vivo whether this hypothesis is correct.
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Notify Me18 year and older
All sexes
Interventional
Phase 1
Leeds, West Yorkshire, LS2 9LU, United Kingdom
The aim is translate our research into a clinical hand-held dental tool that could be used to measure enamel thickness in less curvaceous anterior incisor (front) teeth, and ultimately monitor erosive tooth surface loss (TSL), which mainly occurs on anterior (front) teeth and the occlusal (top) surface of posterior (back) teeth. In this study, quantifying enamel thickness with ultrasound will provide data which will be assessed for reproducibility and to determine whether or not ultrasound is a potentially viable tool to measure and monitor acid erosion of teeth. This would allow dentists to reinforce advice to patients to reduce acidic consumption, and will motivate them to keep whatever is remaining of their 'precious' enamel tissue, which if lost, will necessitate fillings to be made. These fillings will require future repairs and possible remakes, as they have median survival rates of five years.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
A hand-held ultrasound transducer will be placed on a central incisor and enamel thickness measurements recorded
Time frame: 2 weeks
To know if ultrasound can reliably and reproducibly measure enamel thickness in-vivo
Time frame: 2 weeks (concurrent with primary outcome)
To investigate whether ultrasound can be used to reproducibly measure enamel thickness on human incisor teeth in vivo on three separate occasions
University of Leeds
Other
Acronym: UMET
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