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NCT Number: NCT07247929

Postoperative Pain and Swelling After Flap vsFlapless Technique For Mandibular Third Molar Surgery

This randomized controlled trial evaluates postoperative pain and facial swelling following surgical removal of partially impacted mandibular third molars using flap versus flapless techniques. The aim is to determine which method results in lower postoperative morbidity on the second postoperative day.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Watim Medical College&Dental Hospital

Islamabad, 44000, Pakistan

Location status: Recruiting

Location contact

dr huma bajar huma bajar, bds

CONTACT

[email protected]

00923243322292

About this study

Impacted mandibular third molars frequently require surgical extraction, often involving mucoperiosteal flap elevation and bone removal. These steps may contribute to postoperative complications such as pain, swelling, and trismus. Minimally invasive alternatives, including flapless extraction, aim to reduce surgical trauma.

This study compares postoperative pain and swelling after flap versus flapless techniques in patients with partially impacted mesioangular mandibular third molars. Pain will be assessed using a 10-point Visual Analogue Scale (VAS), and swelling will be measured using standardized anthropometric facial measurements. A total of 160 participants will be randomized into two equal groups. All procedures will be performed by a single surgeon to reduce bias.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-45 years
  • Either gender
  • Partially impacted mesioangular mandibular third molar confirmed clinically and radiographically
  • Second episode of pericoronitis
  • Swelling present on the affected side
  • No bone recession or periodontal disease on radiograph

Exclusion criteria

  • HIV or HBV infection
  • Diabetes or other metabolic disorders
  • Bleeding disorders including von Willebrand disease, thalassemia, hemophilia, thrombocytosis, or thrombocytopenia
  • Periapical infection or acute pericoronitis at time of surgery
  • Severe trismus
  • Immunocompromised status

Treatment and study plan

flap technqiue for mandibular third molar extraction Arm A

Procedure

Surgical extraction performed using a mucoperiosteal flap. A Ward's or modified Ward's incision is placed with a No. 15 blade. The flap is elevated to expose bone, followed by bone guttering with a straight fissure bur under saline irrigation. Tooth sectioning is carried out and fragments are removed. The socket is irrigated with saline and the flap is repositioned and sutured with 3-0 black braided silk.

flapless technquie arm b

Procedure

Surgical extraction of partially impacted mandibular third molar without raising a mucoperiosteal flap. Only minimal gingival reflection is performed using a periosteal elevator. Bone guttering and tooth sectioning are carried out using a bur under saline irrigation. Tooth fragments are removed. The socket is irrigated with saline and 0.2% chlorhexidine. No sutures are placed, and the site is allowed to heal by secondary intention

Primary outcomes

  1. postoperative pain score

    Time frame: 2nd postoperative day

    Pain will be assessed on the 2nd postoperative day using the Visual Analogue Scale (VAS) ranging from 0 = no pain to 10 = worst pain. Patients will be instructed to rate their pain by marking a score on the 10-point VAS.

  2. facial swelling measurement

    Time frame: 2nd postoperative day

    Measurements will be recorded in millimeters as:

    A = Gonion-Tragus B = Gonion-Outer canthus C = Gonion-Ala D = Gonion-Angle of mouth E = Gonion-Pogonion

    Total swelling = A + B + C + D + E. This method is described in the Operational Definition section of your synopsis.

Study contacts

Contact information is provided by the study sponsor or research team.

dr huma bajar huma bajar, bds

CONTACT

[email protected]

00923243322292

Sponsors and collaborators

Lead sponsor

Watim Medical & Dental College

Other

Registry information

Official study title

Comparison of Postoperative Pain and Swelling in Flap Versus Flapless Technique for Surgical Removal of Partially Impacted Mandibular Third Molars: A Randomized Controlled Trial

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Nov 25, 2025
Registry last updated
Nov 25, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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