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NCT Number: NCT07330518

Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth

This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular molars.

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Key information

Conditions

Pain (Visceral, Somatic, or Neuropathic) Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

20 year–60 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Watim Medical College & Dental Hospital

Islamabad, Islamabad, Pakistan, 46500, Pakistan

Location status: Recruiting

Location contact

Syed Saad Aftab Mohiuddin, BDS

CONTACT

[email protected]

00923488572003

About this study

Dental extraction of mandibular posterior teeth require buccal mucosa anesthesia for pain free extraction. Conventional buccal nerve block is the commonly used technique for anesthesia of buccal mucosa but often is not effective and requires multiple injections. This study aims to compare coventional buccal nerve block with buccal nerve trunk block on the basis of Efficacy of local anesthesia which will be determined by need for supplemental infiltration: Use of more than 1 anesthesia cartridges during procedure will be labelled as need for supplemental infiltration.

Intraoperative pain perception: It was assessed while giving injection and during extraction of the tooth using the visual analog scale (VAS) scores. Score of more than 4 will be labelled as positive pain perception.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients aged 20 to 60 years
  • Patients of both gender
  • Patient requiring extraction of mandibular molars

Exclusion criteria

  • Pregnant women
  • Pathologies associated with teeth i.e. cysts, tumors
  • Patients on radiotherapy or chemotherapy
  • Patients with mandibular fracture

Treatment and study plan

Conventional Buccal Nerve Block

Procedure

Arm Description: Administration of anesthesia at the level of occlusion lateral to last mandibular molar. Needle is inserted until bone contact is achieved. 1ml lidocaine with 1:100000 anesthesia is administered.

Buccal Nerve Trunk Block

Procedure

Arm Description: Administration of anesthesia 10 mm above occlusal plane lateral to last mandibular molar. 1ml lidocaine with 1:100000 anesthesia is administered.

Primary outcomes

  1. Intraoperative pain perception

    Time frame: Within 2hours of anesthesia administration

    It was assessed while giving injection and during extraction of the tooth using the visual analog scale (VAS) scores. Facial pain scale uses facial expression to evaluate the amount of pain. It has scores ranging from 0 to 10 with 0 as the least pain and 10 as the worst pain. Score of more than 4 will be labelled as positive pain perception.

  2. Need for supplemental infiltration

    Time frame: Within 2 hour of initial anesthesia administration

    Use of more than 1 anesthesia cartridges during procedure will be labelled as need for supplemental infiltration.

Study contacts

Contact information is provided by the study sponsor or research team.

Syed Saad Aftab Mohiuddin

CONTACT

[email protected]

00923488572003

Sponsors and collaborators

Lead sponsor

Watim Medical & Dental College

Other

Registry information

Official study title

Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block for Anaesthesia of Buccal Mucosa During Extraction of Mandibular Posterior Teeth

Acronym: Buccal Trunk

Important dates

Study start
2026
Primary completion
2027
Study completion
2027
First posted
Jan 9, 2026
Registry last updated
Feb 4, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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