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OpenTrials
Completed

NCT Number: NCT02364011

Outcomes Following Total Knee Arthroplasty

The purpose of this investigation is to determine both patient-reported and performance-based outcomes, specifically muscle function and kinematic/kinetic outcomes, between four different surgical total knee prostheses in individuals following TKA. Change scores will be determined based on patient-reported outcomes, kinematic/kinetic data, knee extension strength/power, static/dynamic balance control, mobility measures and functional performance testing during functional tasks (i.e. walking, ascending/descending stairs, sit-to-stand). After evaluating the pattern of change in lower-extremity function, the investigators will be better prepared to address residual functional impairments and prognostic factors linked to maximal recovery over two years.

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Key information

Conditions

Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Rheumatic Diseases

Age range

40 year–90 year

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Utah Orthopaedic Center

Salt Lake City, Utah, 84108, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • adults > 40 years of age that are scheduled for primary TKA
  • if they have had a previous TKA, it needs to have been performed on the opposite leg at least 3 months prior to the current TKA
  • willing to return for follow-up visits and should be willing and able to be transported from the UOC to the Skeletal Muscle Exercise Research Facility (SMERF), in the Department of Physical Therapy study site for scheduled research follow-up appointments

Exclusion criteria

  • adult with previous additional orthopaedic, neurological, visual or surgical conditions that may affect gait or balance

Treatment and study plan

Primary outcomes

  1. Patient Reported Outcome Scores following TKA

    Time frame: Follow Up Visits up to 2-Years

Sponsors and collaborators

Lead sponsor

University of Utah

Other

Registry information

Official study title

Clinical and Biomechanical Outcomes Following Total Knee Arthroplasty

Important dates

Study start
2014
Primary completion
2025
Study completion
2025
First posted
Feb 16, 2015
Registry last updated
Nov 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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