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NCT Number: NCT07250906

Oral Health Related Quality of Life of Children With Amelogenesis Imperfecta

This project aims to evaluate the impact of anterior veneer treatment on oral health-related quality of life in children with amelogenesis imperfecta (AI). AI is an inherited disorder that causes structural defects in enamel due to genetic abnormalities, leading to aesthetic, functional, and psychosocial challenges. Enamel defects, particularly in the anterior teeth, negatively affect patients' self-confidence and social interactions. In this study, the short-term aesthetic, functional, and psychosocial effects of veneer restorations applied to children with AI will be assessed.

This research is designed as a single-center, prospective clinical study. The study population will include pediatric patients aged 11-14 years who have been clinically and radiographically diagnosed with AI at our faculty clinic. Participants' oral health-related quality of life will be evaluated before treatment and one month after treatment using the Child Perceptions Questionnaire (CPQ11-14). Psychosocial improvement will be measured using the Rosenberg Self-Esteem Scale and the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ), while aesthetic satisfaction will be assessed using a Visual Analogue Scale (VAS). In addition, to objectively evaluate the participants' oral hygiene and dental health, the plaque index, gingival index, bleeding on probing index, and DMFT index will be recorded.

The data obtained are expected to demonstrate the positive impact of veneer treatment on the quality of life of children with AI, emphasizing the importance of early aesthetic rehabilitation in pediatric patients. In this respect, the study aims to provide a novel clinical and psychosocial contribution to the existing literature on the management of AI in pediatric dentistry.

Recruiting

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Key information

Age range

11 year–14 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Istanbul University, Faculty of Dentistry, Department of Pedodontics

Istanbul, Turkey (Türkiye)

Location status: Recruiting

Location contact

Yelda Kasımoğlu, Assoc. Prof.

CONTACT

[email protected]

00905336233978

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Systemically healthy,
  • Aged between 11 and 14,
  • Diagnosed with Amelogenesis Imperfecta,
  • Need for anterior veneers,
  • Both female and male volunteers

Exclusion criteria

  • Those with systemic diseases,
  • Those with a history of allergies,
  • Those not diagnosed with Amelogenesis Imperfecta,
  • Those without an indication for veneers,
  • Those lacking adequate cooperation skills,
  • Patients younger than 11 or older than 14 years will not be included in the study.

Treatment and study plan

Veneers

Procedure

Anterior veneer treatment

Primary outcomes

  1. oral health related quality of life

    Time frame: 1 month and 6 months

    CPQ11-14

Secondary outcomes

  1. self esteem

    Time frame: 1 month and 6 months

    Rosenberg Self-Esteem Scale

  2. psychosocial impact of dental aesthetics

    Time frame: 1 month and 6 months

    PIDAQ

  3. hypersensitivity

    Time frame: 3 months

    Wong-Baker scale

  4. oral hygiene

    Time frame: 3 months

    plaque index

  5. gingival health

    Time frame: 3 months

    gingival index

  6. gingival bleeding

    Time frame: 1 month and 6 months

    bleeding on probing

  7. caries status

    Time frame: 1 month and 6 months

    DMFT

Sponsors and collaborators

Lead sponsor

Istanbul University

Other

Registry information

Official study title

Evaluation of the Impact of Anterior Veneers on the Quality of Life of Children With Amelogenesis Imperfecta

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Nov 26, 2025
Registry last updated
May 12, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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