Oat and Cholesterol

Inclusion criteria

• Fasting LDL cholesterol 116-193 mg/dl (3-5 mmol/L)
• Males and non-pregnant, non-lactating females 18-65 years
• Agree to consume the investigational product three times daily for the duration of the study
• BMI 18.5 to 39.9 kg/m2
• Blood pressure <160/100 mmHg
• Fasting triglycerides <4.0 mmol/L
• Fasting serum glucose <126mg/dL (<7 mmol/L)
• Serum urea and creatinine < 1.8 times upper limit of normal (ULN)
• Serum aspartate aminotransaminase (AST), alanine aminotransferase (ALT) and gamma-glutamyl transferase (GGT) < 2 times ULN
• Hemoglobin > 0.9 times lower limit of normal and < 1.1 times ULN
• Have a stable body weight (<7 kg change) over the past 3-months
• Absence of health conditions that would prevent fulfillment of study requirements

Exclusion criteria

• Pregnancy, breastfeeding or planning to be pregnant
• Allergy or sensitivity to study product ingredients
• Dislike description of study product
• Diet containing ≥15% of energy from saturated fat
• Consuming >20g fiber/per 1000 Kcal or >40g fiber/day (including soluble fiber supplements)
• Consumption of more than 2 drinks of alcohol per day, or more than 14 drinks per week
• Extreme dietary habits
• Smoking >5 cigarettes or equivalent per day
• Use of cholesterol lowering medication or prescription drug or for treating diabetes mellitus within 4 weeks of randomization
• Active major gastrointestinal disorder
• Major trauma or hospitalization for a medical condition or major surgical event within 6 months of randomization
• History of cancer within two years or randomization, except for non-melanoma skin cancer
• Any condition or substance use which might, in the opinion of the PI, make participation dangerous for the participant, lead to poor attendance or compliance or affect the results