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OpenTrials
Completed

NCT Number: NCT01154582

Nutritional Quality of Egg Proteins and Effect on Satiety

The project aims to precisely quantify the postprandial amino acid utilization of egg proteins in vivo in humans, and also to assess their satiating power, in relation with nutrient postprandial waves and incretin secretions. For that purpose, 2 independent studies are conducted. The first one is realized using stable isotopes on 8 volunteers ingesting an egg test meal. The second one is a cross over design performed on 30 volunteers to compare the satiating effect of 2 equivalent snacks: whole eggs or cottage cheese.

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Key information

Conditions

Physiology Behavior Behavior, Animal Feeding Behavior Nutrition

Age range

18 year–40 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Centre de recherche sur volontaires, Bobigny, France

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Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy volunteers
  • BMI between 18 and 25

Exclusion criteria

  • Allergy to egg or milk protein
  • Digestive or metabolic pathology
  • Positiveness to HIV, Hepatitis B and C
  • Smokers

Treatment and study plan

Egg snack

Dietary Supplement

subject consume 4 cooked whole eggs, providing 380 kcal

Cottage cheese

Dietary Supplement

Subjects consume 200 g of cottage cheese, providing 380 kcal

Primary outcomes

  1. energy intake at lunch following the snack

  2. Dietary amino acid utilization

    transfer of stables isotopes used as intrinsic markers of egg proteins to metabolic pools

Secondary outcomes

  1. plasma incretin concentrations

    insulin, glucagon, GLP-1, PYY, ghrelin, GIP

  2. postprandial nutrient waves

    plasma glucose, cholesterol, triglyceride, urea

  3. neoglucogenesis

    Endogenous production of glucose and contribution of dietary amino acids

Sponsors and collaborators

Lead sponsor

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement

Other

Collaborators

  • National Research Agency, France

Registry information

Important dates

Study start
2009
First posted
Jul 1, 2010
Registry last updated
Oct 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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