No Need for Neuromuscular Blockade in Daycase Laparoscopic Surgery

This study analyse the need for neuromuscular blockade in consecutive routine laparoscopic procedures without standard use of neuromuscular blockade in an ambulatory laparoscopic surgery setting and analyse specific reasons for using neuromuscular blockade in individual patients. Furthermore, the study report the analgesic use in postoperative care unit and the discharge rate.

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Key information

Conditions

Cholecystitis Biliary Tract Diseases Congenital, Hereditary, and Neonatal Diseases and Abnormalities Digestive System Diseases Gallbladder Diseases Hernia Hernia, Abdominal Hernia, Inguinal Hernia, Umbilical Hernia, Ventral Infant, Newborn, Diseases Inguinal Hernia, Direct Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms Umbilical Hernia

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

The study is retrospective, including consecutive patients in an unrestricted referral of patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair. Inclusion period was from 01.04.2013 to 31.03.2015. All patients received general anesthesia using propofol (2 mg/kg) and remifentanil (1 μg/kg/min) for induction. In patients where tracheal intubation was required, this was done without use of neuromuscular blocking drug; otherwise a proseal laryngeal mask was used. For the maintenance of anesthesia, additional continuous infusion of propofol (3-5 mg/kg/h) and remifentanil (0.3-0.5 μg/kg/min) was used. Data were derived from a prospective local database on demographics, anesthetic methods and supplements (i.e. need for neuromuscular blockade) and postoperative needs for supplementary analgesics besides the postoperative standard analgesic regimen, number of hours stayed in the ambulatory surgery department, and discharge rate (including reasons for hospital admittance).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair

Exclusion criteria

None

Treatment and study plan

Primary outcomes

Number of patients requiring neuromuscular blockade

Time frame: At time of surgery

Data derived from a prospective local database on need for neuromuscular blockade in patients undergoing laparoscopic cholecystectomy, umbilical and inguinal hernia repair.

Secondary outcomes

Analgesic use in postoperative care unit

Time frame: Within 6 hours after surgery

Amount of opioids administered to the patients in the postoperative care unit
Hours stayed in the postoperative care unit

Time frame: 1 to 6 hours after surgery
Maximum Visual analog score (VAS) for pain in the postoperative Care unit

Time frame: 1 to 6 hours after surgery

Sponsors and collaborators

Lead sponsor

Hvidovre University Hospital

Other

Registry information

Official study title

No Need for Neuromuscular Blockade in Day Case Standardised Laparoscopic Surgery. A Consecutive Retrospective Study

Important dates

Study start: 2016
Primary completion: 2016
Study completion: 2016
First posted: May 25, 2016
Registry last updated: May 29, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed