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Completed

NCT Number: NCT02829463

MRI of Infrapatellar Fat Pad in Osteoarthritis

In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis. Differences of MRI data were studied between two groups.

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Key information

Sex eligibility

All sexes

Study type

Observational

Primary location

Jinshen He

Changsha, Hunan, 410011, China

About this study

In this study, the investigators applied high precision MRI technique (with as less as a slice thickness of 0.35 mm and without inter-slice gap), and calculated not only the IPFP maximal sagittal area and IPFP volume, but also the quantitated signal, and compared the differences between healthy controls and osteoarthritis patients. This is an observational cross-sectional study without specific interventions to the subjects. MRI is a regular examination in our hospital. And all subjects are included for the reasons of osteoarthritis (need MRI) and healthy controls (pain but not osteoarthritis, also need MRI). The investigator does not assign specific interventions to the subjects of the study.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with clinical knee osteoarthritis;
  • The healthy controls who require MRI test.

Exclusion criteria

  • Contraindications to magnetic resonance imaging;
  • Rheumatoid arthritis patients;
  • Gout;
  • Hemophilic arthritis;
  • Subjects who take non-steroidal anti-inflammatory drugs (NSAIDs);
  • Subjects who take lipid-lowering agents;
  • Subjects who have the history of knee trauma;
  • Subjects who have the history of knee operation;
  • Subjects who have the disease of musculoskeletal tumor near knee;
  • Subjects who have joint loose bodies.

Treatment and study plan

Magnetic resonance imaging

Radiation

3.0 T Magnetic resonance imaging of knee joints. It does not harm the subjects.

Primary outcomes

  1. Infrapatellar Fat Pad Volume in MRI

    Time frame: collect the data within 24 hours after the subjects did the MRI

Sponsors and collaborators

Lead sponsor

The Third Xiangya Hospital of Central South University

Other

Registry information

Official study title

Magnetic Resonance Imaging of Infrapatellar Fat Pad in Osteoarthritis and Controls

Acronym: IPFP-MRI

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
Jul 12, 2016
Registry last updated
Jun 12, 2017

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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