Ropivacaine and Lidocaine
DrugPopliteal sciatic block using Ropivacaine 100 mg and Lidocaine 100 mg in 20 mL
NCT Number: NCT06671028
Choice of local anesthetics is the major determinant of the characteristics of a peripheral nerve block. Short acting local anesthetics while provides faster onset suffer from shorter duration. On the other hand, long acting local anesthetics while provides long duration suffered from long onset time. The ideal local anesthetics should provide faster nerve block onset while providing reasonable duration to provide sustained postoperative analgesia. Mixing short and long acting local anesthetics for nerve blocks may appear to be the solution however previous published studies have demonstrated similar onset time to long acting local anesthetics and with reduced duration. Recently, the London Health Sciences Centre established an ambulatory surgical centre. Fast onset peripheral nerve block is desirable. Previous studies have not looked at popliteal sciatic block and anecdotally we feel addition of short acting local anesthetics appear to speed up onset. We are therefore interested in conducting a randomize trial to determine whether mixing short and long acting local anesthetics can speed up onset of surgical quality block.
Trial opening soon.
Get Notified18 year and older
All sexes
Interventional
Not applicable
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Popliteal sciatic block using Ropivacaine 100 mg and Lidocaine 100 mg in 20 mL
Popliteal sciatic block using ropivacaine 0.5% 20 mL
Time frame: Tested every 2 min up to 60 min
The primary outcome is onset time for achievement of complete sensory block of the sciatic nerve determined via pinch test.
Time frame: up to 48 hours after discharge
Patient self reported time to onset of pain or analgesics
Time frame: 6 hours after nerve block
Numeric rating scale of patient self-reported pain at 6 hour after block placement
Time frame: at 48 hour
5 point categorical
Contact information is provided by the study sponsor or research team.
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Other
Ropivacaine Versus Ropivacaine With Lidocaine Mixture in Poplitial-Sciatic Nerve Block for Below Knee Surgeries- A Randomized, Single Center Study
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