faculty of physical therapy Cairo university
Dokki, Giza Governorate, Egypt
Location status: Recruiting
Location contact
Ali Ismail, lecturer
CONTACT
Ali MA Ismail, Lecturer
PRINCIPAL_INVESTIGATOR
Recruiting
NCT Number: NCT07130318
Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Aerobic Exercise
Familial Mediterranean fever (FMF) affect liver and causes some dysfunctions including non-alcoholic fatty liver.. still exercise and diet limitation is the treatment for this case
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Age range
30 year–55 year
Sex eligibility
Female
Study type
Interventional
Phase
Not applicable
Primary location
About this study
Familial Mediterranean fever (FMF women with fatty liver) will be collected to be cateogarized to group I or group II. Every group OF FMF will contain 20 FMF women. Both groups will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. Group I will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
- familial Mediterrean fever women
- obese women
- women who have fatty live (non alcoholic type)
Exclusion criteria
- cardiac patients
- respiratory disease
- renal disease
- cancer
Treatment and study plan
exercise plus diet restriction
BehavioralFamilial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months. also, this group, Group I, will also perform elliptical aerobic exercise (this exercise will be applied for 40 minutes three times weekly and this exercise will be maintained for 6 months)
diet restriction
BehavioralFamilial Mediterranean fever (FMF women ) will be collected in this group. the group OF FMF will contain 20 FMF women. the group will follow their colchicine (traditional daily drug therapy for FMF) in addition to Mediterranean diet for six months.
Primary outcomes
-
aspartate transaminase
Time frame: it will be measured after 6 months
it is a hepatic enzyme
Secondary outcomes
-
alanine transaminase
Time frame: it will be measured after 6 months
it is a hepatic enzyme
-
body mass index
Time frame: it will be measured after 6 months
it will be measured after patient emptying his bowel and bladder
-
waist circumference
Time frame: it will be measured after 6 months
it will be measured at umbilical level
-
high density lipoprotein
Time frame: it will be measured after 6 months
it will be measured in plasma
-
triglycerides
Time frame: it will be measured after 6 months
it will be measured in plasma
-
cholesterol
Time frame: it will be measured after 6 months
it will be measured in plasma
-
low density lipoprotein
Time frame: it will be measured after 6 months
it will be measured in plasma
-
c reactive protein
Time frame: it will be measured after 6 months
it will be measured in plasma
-
erythrocyte sedimentation rate
Time frame: it will be measured after 6 months
it will be measured in plasma
Study contacts
Contact information is provided by the study sponsor or research team.
Ali Ismail, lecturer
CONTACT
Ali MA Ismail, lecturer
CONTACT
Sponsors and collaborators
Lead sponsor
Cairo University
Other
Registry information
Official study title
Mediterranean Diet in Familial Mediterranean Fever: Is Fatty Liver Affected by Addition of Elliptical Aerobic Exercise
Important dates
- Study start
- 2025
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Aug 19, 2025
- Registry last updated
- Aug 19, 2025
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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