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NCT Number: NCT07088198

Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture

This study aims to evaluate the functional and surgical outcome of Joshi's step with buccal graft urethroplasty for the management of nearly obliterated bulbar urethral stricture.

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Key information

Age range

18 year and older

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location status: Recruiting

Location contact

Mohamed I Elmaadawy, MD

CONTACT

[email protected]

00201060245430

About this study

Urethroplasty is a rapidly evolving art that continually improves and reinvents itself. After a century of silence, during which the anastomotic repair was the only solution for approaching the strictured urethra, the 1990s can be considered the Renaissance period for reconstructive urology.

In 2022, Joshi and Kulkarni introduced a new step to the augmented urethroplasty, particularly in patients with extremely narrow strictures where a single augmentation was insufficient. They avoid any resection of the residual native urethral plate, marking the narrowest portion. Then, the edges of the mucosa are reapproximated with interrupted suturing in a proper non-resecting approach.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with primary bulbar urethral stricture.
  • Patients with non-traumatic bulbar urethral stricture.
  • Patients with nearly obliterated bulbar urethral stricture, with the narrowest portion of the stricture is less than 1.5 cm in length.

Exclusion criteria

  • Patients with traumatic bulbar urethral stricture.
  • Patients with redo bulbar urethral stricture.
  • Patients with obliterated bulbar urethral stricture.
  • Patients with nearly obliterated long bulbar urethral stricture.

Treatment and study plan

Joshi's step

Procedure

Patients will undergo dorsal onlay buccal mucosal graft urethroplasty with Joshi's step

Primary outcomes

  1. Success rate

    Time frame: 6 months postoperatively

    Incidence of success rate will be recorded.

Secondary outcomes

  1. Urine flow rate

    Time frame: 6 months postoperatively

    Urine flow rate will be recorded.

  2. The urethral lumen

    Time frame: 6 months postoperatively

    The urethral lumen by ascending urethrogram will be recorded.

Study contacts

Contact information is provided by the study sponsor or research team.

Mohamed I Elmaadawy, MD

CONTACT

[email protected]

00201060245430

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Joshi's Step With Buccal Mucosal Graft Urethroplasty in Nearly Obliterated Bulbar Urethral Stricture: A Prospective Study

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Jul 28, 2025
Registry last updated
Jul 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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