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NCT Number: NCT07153861

Oral Mucosal Graft Versus Labial Graft in Female Urethroplasty

This study aims to compare the oral versus labial graft in female urethroplasty in female urethral stricture.

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Key information

Conditions

Oral Mucosal Graft Female Labial Graft Urethroplasty

Age range

18 year and older

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Tanta University

Tanta, El-Gharbia, 31527, Egypt

Location status: Recruiting

Location contact

Mohamed I Elmaadawy, MD

CONTACT

[email protected]

00201060245430

About this study

Female urethral stricture is an uncommon condition with an estimated prevalence of 4%-13% in women with bladder outlet obstruction.

Urethral reconstruction may become the treatment of choice in stricture recurrence following the failure of minimally invasive procedures. and the use of flaps and grafts has all been proposed. Different materials (e.g., vaginal and genital mucosal graft or flap, bladder mucosal flap, and oral mucosal graft) have been reported for augmentation urethroplasty.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female patients with urethral stricture.
  • Female patients with non-traumatic urethral stricture.

Exclusion criteria

  • Female patients with traumatic urethral stricture.
  • Female patients with systemic contraindications of surgery like bleeding disorders.

Treatment and study plan

Oral mucosal graft

Procedure

Patients will be admitted for the surgical management by the oral mucosal graft urethroplasty with the anterior onlay technique.

Labial Graft

Procedure

Patients will be admitted for the surgical management by the labial graft urethroplasty with the anterior onlay technique.

Primary outcomes

  1. Urine flow rate

    Time frame: 6 months post-procedure

    Urine flow rate will be recorded.

Study contacts

Contact information is provided by the study sponsor or research team.

Elmaadawy I Elmaadawy, MD

CONTACT

[email protected]

00201060245430

Sponsors and collaborators

Lead sponsor

Tanta University

Other

Registry information

Official study title

Oral Mucosal Graft Versus Labial Graft in Female Urethroplasty: A Prospective Comparative Study

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Sep 4, 2025
Registry last updated
Sep 4, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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