CHU de Rennes
Rennes, 35033, France
Location status: Recruiting
NCT Number: NCT05887440
The purpose of this study is to assess the impact of an isokinetic strength training of knee flexor and extensor muscles on walking performance in hemiparetic patients with knee extension thrust.
Interested in participating?
Request Info18 year–75 year
All sexes
Interventional
Not applicable
Rennes, 35033, France
Location status: Recruiting
The study will be interventional single case experimental design (SCED) with multiple baseline design. SCED are experimental designs aiming at testing the effect of an intervention using a small number of patients using repeated measurements, sequential and randomized introduction of an intervention and method-specific data analysis, including visual analysis and specific statistics.
During baseline, patients will have a rehabilitation program in day hospital (4 days per week) with physiotherapy and physical activity and if necessary occupational and speech therapy. Isokinetic strength training will be added to this conventionnal rehabilitation program and will begin after 3, 4 or 5 weeks of baseline according to randomization
12 patients will be included in this study (6 patients in subacute stage and 6 in chronic stage ).
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Patients underwent an isokinetic strength training program with 3 sessions per week during five weeks.
Program consists of excentric contraction of knee flexor and extensor muscles (4 x 7 Contractions at 30°/s) and concentric contractions at maximal speed where patients can perform 40% of his maximal isometric torque for knee flexor and extensor muscles (2x10 for knee flexors and 2x10 for knee extensors)
Time frame: 25 weeks
Spontaneous walking speed of hemiparetic patients recorded with 3D gait analysis
Time frame: 25 weeks
Extensor thrust at spontaneous and maximal walking speed and during dual task recorded with 3D gait analysis
Time frame: 25 weeks
assessment of walking speed in two conditions (maximal speed and dual task)
Time frame: 25 weeks
time to ascend and descend stairs (maximal speed)
Time frame: 25 weeks
time to walk in an inclined plan (maximal speed)
Time frame: 25 weeks
Assessment of maximum gait perimeter during a 6MWT (6-minute walk test :6MWT)
Time frame: 25 weeks
1 minute sit to stand test (number of repetitions)
Time frame: 25 weeks
Extensor thrust analysis with inertial measurement unit (stairs, inclined walk, 6MWT and sit to stand )
Time frame: 25 weeks
Fatigue severity scale : FSS (minimum 9 -maximum 63 ; a higher score means higher level of fatigue)
Time frame: 25 weeks
self perception of walking stability, fear of fall, trouble with extensor thrust with a likert scale
Time frame: 25 weeks
strength of knee flexor and extensor muscles assessed with isokinetic dynamometer
Contact information is provided by the study sponsor or research team.
Rennes University Hospital
Other
Effects of Isokinetic Strength Training of Knee Flexor and Extensor Muscles on Walking in Hemiparetic Patients With Knee Extension Thrust
Acronym: ISOWALK
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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