Investigation of the Relationship Between Blood Transfusion Volume and Development of Renal Failure in Pediatric Patients Undergoing Cardiovascular Surgery

Blood transfusion strategies in cardiac surgery are a research topic that has been studied more for adults. There is not enough data on this subject for children in studies. Investigators aim to examine the renal damage risk level of blood transfusion volume, which is one of the modifiable risk factors that can cause acute kidney injury in pediatric cases undergoing cardiac surgery.

The main question it aims to answer is:

What is the effect of blood transfusion volume on the risk of renal damage in pediatric cardiovascular surgery? The names of the patients who were operated on by the Department of Cardiovascular Surgery will be accessed from the system records and their files will be reviewed. The patients' demographic information, anesthesia management and postoperative renal function tests will be scanned.

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Key information

Conditions

Congenital Cardiac Defect Acute Kidney Injury Acute Renal Injury Blood Transfusion Complication Cardiovascular Abnormalities Cardiovascular Diseases Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Heart Defects, Congenital Heart Diseases Hematologic Diseases Hemic and Lymphatic Diseases Immune System Diseases Kidney Diseases Male Urogenital Diseases Renal Insufficiency Transfusion Reaction Urogenital Diseases Urologic Diseases

Age range

Up to 18 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Hacettepe University Anesthesiology and Reanimation

Ankara, Turkey (Türkiye)

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

pediatric patients undergoing cardiovascular surgery

Exclusion criteria

Being over 18 years old Weighting over 30 kg Preoperative acute kidney injury

Treatment and study plan

Blood transfusion

Other

Red blood cell suspension replacement during surgery

Primary outcomes

postoperative acute renal failure

Time frame: From registration to the end of the second postoperative day

Sponsors and collaborators

Lead sponsor

Hacettepe University

Other

Registry information

Important dates

Study start: 2024
Primary completion: 2024
Study completion: 2024
First posted: Mar 21, 2025
Registry last updated: Mar 21, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed