Guy's and St. Thomas NHS Foundation Trust
London, SE1 7EH, United Kingdom
Location status: Recruiting
Recruiting
NCT Number: NCT04236726
Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
Recruiting
Interested in participating?
Request InfoKey information
Conditions
Chronic Obstructive Pulmonary Disease
Chronic Disease
Disease Attributes
Hypoventilation
Lung Diseases
Lung Diseases, Obstructive
Nervous System Diseases
Neuromuscular Diseases
Pathologic Processes
Pathological Conditions, Signs and Symptoms
Pulmonary Disease, Chronic Obstructive
Respiration Disorders
Respiratory Failure
Respiratory Insufficiency
Respiratory Tract Diseases
Signs and Symptoms
Signs and Symptoms, Respiratory
Ventilatory Failure
Age range
18 year and older
Sex eligibility
All sexes
Study type
Observational
Primary location
About this study
To determine the quality of life of patients living with chronic respiratory failure and the impact interventions have on it.
Who can participate
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Diagnosed with chronic respiratory failure receiving any of:
- Non-invasive ventilation
- Prolonged mechanical ventilation
- Mechanical insufflation-exsufflation therapy
Exclusion criteria
- Aged <18
- Significant physical or psychiatric co-morbidity that would prevent compliance with trial protocol
Treatment and study plan
Questionnaire
OtherHRQoL questionnaires
Primary outcomes
-
HRQoL score
Time frame: Day 0: At the first outpatient clinical consultation with the clinical team
Outcome of various HRQoL assessment tools.
Secondary outcomes
-
Change in HRQoL score
Time frame: 6 months following first assessment for Outcome 1
Change in HRQoL assessment tool score at next clinical follow-up.
Study contacts
Contact information is provided by the study sponsor or research team.
Neeraj Shah, MBBS
CONTACT
Patrick Murphy, MBBS
CONTACT
Sponsors and collaborators
Lead sponsor
Guy's and St Thomas' NHS Foundation Trust
Other
Registry information
Acronym: CRF-QoL
Important dates
- Study start
- 2019
- Primary completion
- 2026
- Study completion
- 2026
- First posted
- Jan 22, 2020
- Registry last updated
- Jun 4, 2026
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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