Interventional X-ray and Scintigraphy Imaging of 99mTc-MAA During the Radioembolisation Pretreatment Procedure

Inclusion criteria

• Participants must have given written informed consent and comply with the requirements of the study protocol.
• Must be aged 18 years or over.
• Must be selected to undergo a 99mTc-MAA procedure as part of their radioembolisation treatment.
• Sufficiently fit to undergo an additional examination time of 30-90 minutes.
• Have a CT acquired less than 6 weeks before the pre-treatment radioembolisation procedure.

Exclusion criteria

• Patients expected to require more than two injection positions for radioembolisation treatment.
• Pregnancy or nursing.
• Patients suffering from psychic disorders that make a comprehensive judgement impossible, such as psychosis, hallucinations and/or depression.
• Patients who are declared incompetent.
• Previous enrollment in the present study
• Claustrophobia
• The last dose of prior chemotherapy has been received less than weeks prior to the planned 99mTc-MAA pre-treatment procedure.
• Radiation therapy within the last 4 weeks before the planned 99mTc-MAA pre-treatment procedure
• Major surgery within the last 4 weeks prior to the planned 99mTc-MAA pre-treatment procedure
• Any unresolved toxicity greater than Common Terminology Criteria for Adverse Events (CTCAE version 5) grade 2 from previous anti-cancer treatment
• Body weight over 250 kg (because of maximum table load)
• Patient length over 1.90 m (to fit IXSI geometry)
• Patient bust line over 135 cm (to fit IXSI geometry)