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Completed

NCT Number: NCT06953947

Interscalene Versus Costoclavicular Blocks for Shoulder Surgery

AIM: Shoulder surgeries are among the most painful surgical procedures in orthopedic practice. Interscalene brachial plexus block, although the most commonly utilized regional anesthesia technique for alleviating pain following shoulder surgery, may result in complications such as hemidiaphragmatic paresis, hoarseness. More distal blocks along the brachial plexus may provide postoperative analgesia while potentially having less effect on respiratory functions. The aim of this study is to determine whether there are differences in postoperative pain scores and opioid consumption between interscalene block (ISB) and costoclavicular brachial plexus block (CCB).

MATERIALS AND METHODS: Following ethical approval, all eligible patients undergoing for shoulder surgery under general anesthesia between 01.11.2022 and 01.11.2023 will be enrolled and to be divided into two groups following written informed consent, with one group receiving ISB and the other group receiving CCB. A blinded researcher will record pain scores at postoperative 0.5, 1, 6, 12, 18, and 24 hours. Demographic data of patients, postoperative opioid consumption, time to first analgesic request, rescue analgesic requirements, adverse effects and hemodynamic parameters will be compared statistically.

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Key information

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Sakarya University Training and Research Hospital

Sakarya, 54290, Turkey (Türkiye)

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients undergoing unilateral shoulder surgery
  • ASA (American Society of Anesthesiology) class I, II and III patients

Exclusion criteria

  • Coagulopathy
  • Chronic Pulmoner Disease
  • Hypersensitivity to local anesthetics
  • Ipsilateral neurological deficits
  • Non-communicative patients

Treatment and study plan

Costoclavicular block

Procedure

The costoclavicular block was first described by Karmakar et al. in 2015. It is a type of brachial plexus block that targets the three cords located lateral to the axillary artery within the costoclavicular space. The costoclavicular space is defined as the area between the middle third of the clavicle and the anterior thoracic wall. Within this space, the cords of the brachial plexus are situated lateral to the axillary artery, positioned between the pectoralis major, subclavius, and serratus anterior muscles.

In contrast to the traditional infraclavicular approach, the cords in the costoclavicular block are located more superficially and are more consistently clustered lateral to the axillary artery, which may facilitate visualization and needle targeting. After the needle is placed between the three cords under ultrasound guidance, the local anesthetic (20 mL of 0.25% bupivacaine) is injected.

interscalene block

Procedure

Originally described by Etienne in 1925, the technique was later refined into its modern clinical form by Alon Winnie in 1970. The interscalene approach, primarily preferred for shoulder surgeries, aims to target the upper roots of the brachial plexus (C5-C7). In interscalene block, a needle is placed under ultrasound guidance around the upper and middle trunks of the brachial plexus, which pass through the space between the anterior and middle scalene muscles, and the local anesthetic (20 mL of 0.25% bupivacaine) is injected while its spread is observed.

Costoclavicular block

Drug

In costoclavicular block, the course of the three cords of the brachial plexus is visualized under ultrasound guidance, adjacent to the brachial artery beneath the clavicle. Subsequently, after the needle is placed under ultrasound guidance between the three cords, 20 mL of 0.25% bupivacaine is injected as the local anesthetic.

interscalene nerve block

Drug

In interscalene block, using an ultrasound probe placed on the neck, the course of the brachial plexus trunks between the anterior and middle scalene muscles is visualized. Then, after the needle is inserted under ultrasound guidance between the anterior and middle scalene muscles, 20 mL of 0.25% bupivacaine is injected as the local anesthetic.

Primary outcomes

  1. Postoperative Pain Measurement

    Time frame: Measured at Postoperative 0.5, 1, 6, 12, 18, and 24 hours

    The pain measurements of the patients after surgery which evaluated with visual analogue scale (VAS), ranging from 0 to 10 while 0 describes no pain at all and 10 describes the most severe pain a person can experience.

Secondary outcomes

  1. Postoperative Opioid Consumption

    Time frame: Postoperative 24 hours.

    The total amount of opioid analgesics used which measured by the patient controlled analgesia (PCA) device for the postoperative 24 hours

  2. Time to first analgesic request

    Time frame: Postoperative 24 hours

    The period of time which describes the patient's first postoperative analgesic request.

  3. Rescue analgesic requirements

    Time frame: Postoperative 24 hours

    The drugs that used for additinoal analgesia.

  4. Adverse effects

    Time frame: Postoperative 24 hours

    Any adverse effects related to anesthetic and analgesic procedures.

Sponsors and collaborators

Lead sponsor

Sakarya University

Other

Registry information

Official study title

A Comparison Between Interscalene and Costoclavicular Blocks for Pain Relief After Shoulder Surgery

Important dates

Study start
2022
Primary completion
2024
Study completion
2024
First posted
May 1, 2025
Registry last updated
May 1, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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