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OpenTrials
Completed

NCT Number: NCT06766981

Infiltration Anesthesia vs. Block Anesthesia

Checking the effectiveness of the infiltration technique of local anesthetic agent as an alternative to inferior dental nerve block during tooth extraction

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Key information

Conditions

Tooth Extraction

Age range

18 year–58 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

College of Dentistry, University of Babylon, Hillah, Babylon, Iraq

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About this study

Patients who need their Mandibular first Molar to be removed under local anaesthesia. The first group will receive 4% articaine with 1:100,000 epinephrine as lingual and buccal infiltration. In comparison, the second group will receive a conventional inferior alveolar nerve block technique with 2% lidocaine with epinephrine (1:80,000). Pain will be measured para-operatively using a verbal rating scale.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • The systemic condition must be normal.
  • Patient has no cardiovascular, metabolic, or transmitted disease.
  • The patient has a Mandibular 1st. Molar tooth indicated for extraction.
  • The tooth is non-restorable.

Exclusion criteria

  • Chronic cardiovascular condition, metabolic, or infectious disease.
  • Pregnant women.
  • The tooth is restorable.

Treatment and study plan

Infiltration with Articain 4%

Procedure

The experimental group of patients that are diagnosed for tooth extraction of mandibular 1st. molar will undergo extraction using an infiltration technique for local anaesthesia. In contrast to the conventional group that will receive Inferior alveolar nerve block

Inferior Alveolar Nerve Block

Procedure

This group will receive a conventional inferior alveolar nerve block (IANB) technique with 2% lidocaine with epinephrine (1:80,000) for tooth extraction.

Other names: Regional Anaesthesia

Primary outcomes

  1. Verbal Pain Rating Scale

    Time frame: during the intervention/procedure/surgery

    Pain during tooth extraction will be measured immediately after the procedure is completed using a verbal rating scale. The zero rate will be given when the patient feels no pain; the rating degree will increase as the pain severity becomes more severe. According to the following scale:

    0 No hurt

    • Slight pain
    • Moderate pain
    • Intense pain
    • Extremely painful

Sponsors and collaborators

Lead sponsor

Sinan A. Shwailiya

Other

Collaborators

  • Babylon University

Registry information

Official study title

Effectiveness of Local Anesthetic Infiltration With Articaine 4% in Comparison to Inferior Alveolar Nerve Block With Lidocaine 2% for Mandibular 1st Molar Extraction

Acronym: LAI

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Jan 9, 2025
Registry last updated
Apr 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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