Incidence and Risk of Influenza in Myasthenic Patients

Upper respiratory infection , including influenza, may exacerbate the symptoms of myasthenia gravis (MG), which is an autoimmune disease that causes muscle weakness and, in some cases, can precipitate a myasthenic crisis

In the present study, we investigated the incidence and risk factors of influenza infection on in myasthenia gravis patients.

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Key information

Conditions

Myasthenic Crisis Autoimmune Diseases Autoimmune Diseases of the Nervous System Immune System Diseases Infections Myasthenia Gravis Neoplasms Neoplasms by Site Nervous System Diseases Nervous System Neoplasms Neurodegenerative Diseases Neuromuscular Diseases Neuromuscular Junction Diseases Paraneoplastic Syndromes Paraneoplastic Syndromes, Nervous System Respiratory Tract Diseases Respiratory Tract Infections Upper Respiratory Infection

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

About this study

This is a descriptive study. The data will be analyzed retrospectively . Inclusion of 416 cases of influenza in myasthenic patients treated in the intensive care unit of Garches Hospital between January 1, 2009 and December 31, 2017.

Patients who meet the inclusion and non inclusion criteria and do not object to participate in the study will be collected in a database for analysis.

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Men or women over the age of 18.
Myasthenic patients hospitalized in intensive care.
Patients with confirmed influenza infection

Exclusion criteria

Age <18 years,
Other neuromuscular diseases,
Patient opposing the use of his data

Treatment and study plan

Primary outcomes

Incidence of influenza in myasthenic patient in crisis

Time frame: between January 1, 2009 and December 31, 2017.

Number of influenza cases in myasthenic patients

Secondary outcomes

Risk factors for poor outcomes

Time frame: between January 1, 2009 and December 31, 2017.

To identify risk factors for severe influenza in myasthenic patients

Sponsors and collaborators

Lead sponsor

Centre d'Investigation Clinique et Technologique 805

Other

Registry information

Official study title

Incidence and Risk of Influenza in Myasthenic Patients Hospitalized in Intensive Care

Important dates

Study start: 2009
Primary completion: 2017
Study completion: 2017
First posted: Mar 21, 2019
Registry last updated: Mar 21, 2019

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed