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Clinical trial condition

Neuromuscular Junction Diseases

Explore clinical trials studying Neuromuscular Junction Diseases. Study availability and eligibility vary by location and protocol.

296 public trials 100 recruiting studies
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Neuromuscular Junction Diseases trial results

Recruiting

A Natural History Study in Participants With Congenital Myasthenic Syndromes (CMS) Due to Mutations in DOK7, MUSK, AGRN, or LRP4

NCT06078553

Conditions
Congenital Myasthenic Syndrome, Congenital, Hereditary, and Neonatal Diseases and Abnormalities, Genetic Diseases, Inborn, +4 more
Locations
  • UC Davis Health - UC Davis Health Midtown Ambulatory Care Center Sacramento, California, United States
  • Ann and Robert H Lurie Children's Hospital of Chicago - Main Hospital Chicago, Illinois, United States
  • Hospital Sisters Health System (HSHS) - St Elizabeth's Hospital O'Fallon, Illinois, United States
  • Harvard Medical School - Boston Children's Hospital Boston, Massachusetts, United States
View all 33 locations
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Recruiting

Comparative Efficacy of Nipocalimab and Efgartigimod in Participants With Generalized Myasthenia Gravis

NCT07217587

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Immune System Diseases, +10 more
Locations
  • Neurology Center of North Orange County Fullerton, California, United States
  • The Neurology Group Pomona, California, United States
  • Advanced Neurology of Colorado Fort Collins, Colorado, United States
  • University of Connecticut Farmington, Connecticut, United States
View all 19 locations
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Recruiting

A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Ocular Myasthenia Gravis

NCT07463521

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Immune System Diseases, +11 more
Locations
  • Mg0038 10106 Amherst, New York, United States
  • Mg0038 10103 Columbus, Ohio, United States
  • Mg0038 10104 Scottsdale, Arizona, United States
  • Mg0038 10105 O'Fallon, Illinois, United States
View all 14 locations
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Recruiting

ADAPT Forward - Master Protocol of a Platform Study to Evaluate the Safety and Efficacy of Multiple Regimens in Participants With Myasthenia Gravis

NCT07294170

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +15 more
Locations
  • Profound Research LLC - Carlsbad Carlsbad, California, United States
  • Visionary Investigators Network Miami, Florida, United States
  • University of South Florida Tampa, Florida, United States
  • Henry Ford Health System Detroit, Michigan, United States
View all 36 locations
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Recruiting

ADAPT Forward 1 - ISA1 - a Study to Evaluate Empasiprubart IV as add-on Therapy to Efgartigimod IV in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis With a Partial Clinical Response to Efgartigimod

NCT07284420

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +15 more
Locations
  • Profound Research LLC - Carlsbad Carlsbad, California, United States
  • Visionary Investigators Network Miami, Florida, United States
  • University of South Florida Tampa, Florida, United States
  • Henry Ford Health Systems Detroit, Michigan, United States
View all 33 locations
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Recruiting

ADAPT Forward 2 - ISA2 - a Study to Evaluate the Safety, Tolerability and Efficacy of Empasiprubart IV Monotherapy in Participants With AChR-Ab Seropositive Generalized Myasthenia Gravis

NCT07673627

Conditions
AChR-Ab Seropositive Generalized Myasthenia Gravis, Autoimmune Diseases, Autoimmune Diseases of the Nervous System, +14 more
Locations
  • Visionary Investigators Network Miami, Florida, United States
  • Erlanger Health System Chattanooga, Tennessee, United States
  • Dent Neurologic Institute - Amherst Amherst, New York, United States
  • National Neuromuscular Research Institute Austin, Texas, United States
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Recruiting

A Study of Efgartigimod PH20 SC in Children Between 2 and Less Than 18 Years of Age With Generalized Myasthenia Gravis

NCT06392386

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Generalized Myasthenia Gravis, +11 more
Locations
  • Carolinas HealthCare System Neurosciences Institute - Neurology Charlotte, North Carolina, United States
  • Neurology Rare Disease Center Denton, Texas, United States
  • University of Virginia Charlottesville, Virginia, United States
  • UZ Gent Ghent, Belgium
View all 22 locations
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Recruiting

A Study to Evaluate the Efficacy and Safety of Maintenance Ublituximab Following Induction With Efgartigimod Administration in Participants With Myasthenia Gravis (MG)

NCT07673744

Conditions
Autoimmune Diseases, Autoimmune Diseases of the Nervous System, Immune System Diseases, +10 more
Locations
  • TG Therapeutics Investigational Trial Site Colorado Springs, Colorado, United States
  • TG Therapeutics Investigational Trial Site Clearwater, Florida, United States
  • TG Therapeutics Investigational Trial Site Colorado Springs, Colorado, United States
  • TG Therapeutics Investigational Trial Site Farmington Hills, Michigan, United States
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