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Completed

NCT Number: NCT04938791

Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults

The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.

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Key information

Conditions

Fatigue Pathologic Processes Pathological Conditions, Signs and Symptoms Respiration Disorders Respiratory Aspiration Respiratory Tract Diseases Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Escola Superior de Saúde da Cruz Vermelha Portuguesa - Lisboa

Lisbon, 1300-125, Portugal

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Healthy
  • Minimum age of 18 years;

Exclusion criteria

  • Unable to provide written consent
  • History of heart, cardiovascular and / or respiratory disease,
  • Known untreated hypertension, cardiomyopathy, or exercise intolerance
  • Presence of cognitive or neurological disorders
  • Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position
  • BMI ≥ 40

Treatment and study plan

Isometric activity

Other

Participants will do elevation of upper limbs and mantain a 90º degree flexion position in an unsupported way.

Other names: Isometric task

Primary outcomes

  1. Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10)

    Time frame: From baseline to end of activity, up to 15 minutes

    The perceived effort will be measured with Borg CR 10 scale. Possible scores range from 0 (no exertion at all) to 10 (extremely strong).

  2. Change from Baseline in heart rate

    Time frame: From baseline to end of activity, up to 15 minutes

    Heart rate (heart beatings per minute) measured before and during activity to track cardiovascular changes during activity.

  3. Change from Baseline in respiratory rate

    Time frame: From baseline to end of activity, up to 15 minutes

    Respiratory rate (respiratory cycles per minute) measured before and during activity to track changes in respiratory function during activity.

  4. Change from Baseline in heart rate variability (HRV)

    Time frame: From baseline to end of activity, up to 15 minutes

    Interval (in milliseconds) between consecutive heartbeats measured before and during activity to track changes in autonomic function during activity.

  5. Change from Baseline in electrodermal activity (EDA)

    Time frame: From baseline to end of activity, up to 15 minutes

    Electrical conductance (in microsiemens -µS) between two points of the hand over time measured before and during activity to track changes in autonomic function during activity.

  6. Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG)

    Time frame: From baseline to end of activity, up to 15 minutes

    Muscle action potential amplitude (in millivolts - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  7. Change from Baseline in muscle action potential duration through surface electromyography (sEMG)

    Time frame: From baseline to end of activity, up to 15 minutes

    Muscle action potential duration (in milliseconds - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  8. Change from Baseline in muscle action potential frequency through surface electromyography (sEMG)

    Time frame: From baseline to end of activity, up to 15 minutes

    Muscle action potential frequency (in hertz - Hz) of surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  9. Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activity

    Time frame: From baseline to end of activity, up to 15 minutes

    Angular range of motion (in degrees) of rib cage and abdominal wall during upper limb activity measured before and during activity to track changes in respiratory pattern during activity

  10. Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) system

    Time frame: From baseline to end of activity, up to 15 minutes

    Angular acceleration (in m/s^2) of the arm measured before and during activity to track small movements of upper limb during isometric activity

Secondary outcomes

  1. Health Status

    Time frame: Before isometric activity

    Health Status will be measured with Medical Outcomes Study (MOS) Short Form Health Survey 36 Item version 2 which measure health status of populations and individuals. Possible scores range from 0 0 (worst health status) to 100 (best health status).

  2. Physical activity level

    Time frame: Before isometric activity

    Physical activity level will be measured using European Prospective Investigation into Cancer and Nutrition Physical Activity Questionnaire (EPIC-PAQ) that allows to estimate energy expenditure through self-report assessment of the intensity and average duration (per day, week and month) of physical activity performed by the participants in three distinct dimensions (professional, domestic and leisure).

    Participants are classified as ACTIVE if they perform: at least 150 minutes per week of moderate physical activity; OR at least 75 minutes per week of vigorous physical activity; OR at least 150 minutes per week of a combination of moderate-intensity activity. If they don't present any of the conditions described, they will be categorized as SEDENTARY.

Sponsors and collaborators

Lead sponsor

Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa

Other

Registry information

Official study title

Relationship Between Perceive Effort, Physiological and Kinematic Changes During Upper Limbs Isometric Activity and Its Relationship With the Socio-demographic Characteristics

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jun 24, 2021
Registry last updated
Mar 31, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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