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Completed

NCT Number: NCT07738744

A Clinical Trial to Evaluate the Effects of a Supplement on Symptoms Associated With Liver and Digestive Health

This study will evaluate the effects of Edenboost Alpha Cleanse, a dietary supplement, on symptoms associated with liver and digestive health. The study is a single-arm, open-label trial in which all 40 enrolled participants will use the test product daily for 12 weeks.

Participants will complete questionnaires at Baseline, Week 4, Week 8, and Week 12, and will undergo blood testing (hepatic function panel) at Baseline and Week 12. Primary outcomes focus on changes in liver function biomarkers, while secondary outcomes capture participants' self-reported experiences of energy levels, abdominal bloating, abdominal pain, fatigue, and nausea.

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Key information

Conditions

Liver Health Abdominal Bloating Abdominal Pain Digestive Health Energy Levels Fatigue Nausea Neurologic Manifestations Pain Pathological Conditions, Signs and Symptoms Signs and Symptoms Signs and Symptoms, Digestive

Age range

40 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Citruslabs

Las Vegas, Nevada, 89118, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Be male or female.
  • Be aged 40-65.
  • Anyone who has struggled with low energy levels and fatigue over the past four weeks.
  • Anyone who has struggled with at least two of the following symptoms over the past four weeks: abdominal bloating, abdominal discomfort, constipation, diarrhea, digestive discomfort.
  • Willing to maintain the same diet, sleep pattern, and exercise regimen consistently throughout the study duration.
  • If taking any other supplements, medications, or herbal remedies, has been doing so consistently for at least three months and is willing to maintain this routine for the duration of the trial.
  • Willing to avoid introducing any other supplements, medications, or herbal remedies for the duration of the trial.
  • Resides in the United States.

Exclusion criteria

  • Anyone with pre-existing chronic conditions that would prevent participants from adhering to the protocol, including mental health disorders, a history of serious illness in the last three months, a history of substance abuse, or planned surgery during the study period.
  • Anyone with a known history of severe digestive disorders like acid reflux, peptic ulcers, Irritable Bowel Syndrome (IBS), Irritable Bowel Disease (IBD), GI bleeding, Crohn's disease, Ulcerative Colitis (UC), or gastrointestinal tract surgeries.
  • Anyone with a history of kidney stones.
  • Anyone with any allergies or sensitivities to any of the study product ingredients.
  • Any women who are pregnant, breastfeeding, or trying to conceive (or who will be at any point during the study period).
  • Anyone on Coumadin (warfarin) or antiplatelet therapy (e.g., Plavix (clopidogrel), aspirin).
  • Anyone with uncontrolled chronic disease, including but not limited to diabetes, hypertension (high blood pressure), and thyroid-related conditions.
  • Anyone unwilling to follow the study protocol.
  • Anyone who is currently a smoker or has been a smoker in the past 3 months.
  • Currently partaking in another research study or will be partaking in any other research study at any point during this study's duration.

Treatment and study plan

Edenboost Alpha Cleanse

Dietary Supplement

All participants receive Edenboost Alpha Cleanse (two capsules once daily with the first meal of the day) for 12 weeks.

Primary outcomes

  1. Change in Alanine Aminotransferase (ALT/SGPT)

    Time frame: Baseline and Week 12

    Change in serum ALT/SGPT level assessed via hepatic function panel blood test at Labcorp

  2. Change in Albumin

    Time frame: Baseline and Week 12

    Change in serum albumin level assessed via hepatic function panel blood test at Labcorp

  3. Change in Alkaline Phosphatase

    Time frame: Baseline and Week 12

    Change in serum alkaline phosphatase level assessed via hepatic function panel blood test at Labcorp

  4. Change in Aspartate Aminotransferase (AST/SGOT)

    Time frame: Baseline and Week 12

    Change in serum AST/SGOT level assessed via hepatic function panel blood test at Labcorp

  5. Change in Bilirubin

    Time frame: Baseline and Week 12

    Change in serum bilirubin level assessed via hepatic function panel blood test at Labcorp

  6. Change in Total Protein

    Time frame: Baseline and Week 12

    Change in serum total protein level assessed via hepatic function panel blood test at Labcorp

Secondary outcomes

  1. Change in Self-Reported Abdominal Bloating

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Participant-reported change in abdominal bloating assessed via self-reported questionnaire

  2. Change in Self-Reported Abdominal Pain

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Participant-reported change in abdominal pain assessed via self-reported questionnaire

  3. Change in Self-Reported Fatigue

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Participant-reported change in fatigue assessed via self-reported questionnaire

  4. Change in Self-Reported Nausea

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Participant-reported change in nausea assessed via self-reported questionnaire

  5. Change in Self-Reported Energy Levels

    Time frame: Baseline, Week 4, Week 8, and Week 12

    Participant-reported change in energy levels assessed via self-reported questionnaire

Sponsors and collaborators

Lead sponsor

Edenboost

Industry

Collaborators

  • Citruslabs

Registry information

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 31, 2026
Registry last updated
Jul 31, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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