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Completed

NCT Number: NCT05271201

Exercise Intensity for Down Syndrome Children

The current study aimed to determine the appropriate exercise intensity for the rehabilitation of children with down syndrome.

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Key information

Conditions

Down Syndrome Abnormalities, Multiple Chromosome Disorders Congenital Abnormalities Congenital, Hereditary, and Neonatal Diseases and Abnormalities Genetic Diseases, Inborn Intellectual Disability Nervous System Diseases Neurobehavioral Manifestations Neurologic Manifestations

Age range

8 year–12 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

College of Applied Medical Sciemces

Ta'if, Mecca Region, 2425, Saudi Arabia

About this study

Two groups of down syndrome children were recruited. one group received mild-intensity treadmill training while the other received moderate-intensity treadmill training. Eccentric knee extensors and ankle plantar flexors peak torques were assessed before and after the intervention. Also, functional mobility was assessed for both groups before and after the intervention. The within and between-subjects effect was used to analyze the obtained data before and after the intervention. isokinetic dynamometer and the time up and go test were used for evaluation.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • independent walking
  • Intelligence quotient range from 40 to 70
  • right dominant foot
  • body mass index from 50 to 75

Exclusion criteria

  • chronic diseases
  • congenital anomalies
  • involved in any competitive sport
  • previous injury to the lower limb

Treatment and study plan

treadmill exercise (mild)

Other

mild intensity treadmill training.

treadmill exercise (moderate)

Other

moderate-intensity treadmill training

Primary outcomes

  1. knee extensor peak torque

    Time frame: three months

    eccentric normalized peak torque of the knee extensors of the dominant limb.

  2. ankle plantar fexors peak torque

    Time frame: three months

    eccentric normalized peak torque of the ankle plantar flexors of the dominant limb.

  3. functional mobility

    Time frame: three months

    the assessment of the time up and go test

Sponsors and collaborators

Lead sponsor

Taif University

Other

Registry information

Official study title

Effect of Exercise Intensity on Knee and Ankle Joints' Torque and Functional Mobility in Children With Down's Syndrome: a Randomized Controlled Trial

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Mar 8, 2022
Registry last updated
Mar 8, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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