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OpenTrials
Completed

NCT Number: NCT04381390

Egg Consumption and Muscular Adaptations

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality.

The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

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Key information

Conditions

Hypertrophy Pathological Conditions, Anatomical Pathological Conditions, Signs and Symptoms

Age range

18 year–30 year

Sex eligibility

Male

Study type

Interventional

Phase

Not applicable

Primary location

Marymount University

Arlington, Virginia, 22207, United States

About this study

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to:

To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • performing resistance training at least three times a week for 1 year prior to the start of the study
  • not taking any dietary supplements or medications for at least 1 year prior to the start of the study
  • no known medical issues
  • no alcohol consumption or smoking for at least 1 year prior to the start of the study
  • no egg allergy/sensitivity.

Exclusion criteria

  • non-willingness to continue nutritional or exercise protocols
  • participation in exercise other than the prescribed resistance training program
  • consumption of dietary supplement (other than egg) during the study period
  • Missing more than one resistance training session or post-exercise egg consumption throughout the study period

Treatment and study plan

Whole egg and resistance training

Dietary Supplement

This intervention consisted of whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.

Egg whites and resistance training

Dietary Supplement

This intervention consisted of egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Primary outcomes

  1. Circulatory Myokines levels

    Time frame: 12 weeks

    Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-β1 and ACVA.

  2. Circulatory hormone levels

    Time frame: 12 weeks

    Fasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol

  3. Muscle mass

    Time frame: 12 weeks

    Skeletal muscle mass will be evaluated using computed tomography

  4. Body fatness

    Time frame: 12 weeks

    Body fat will be evaluated using bioelectrical impedance

Secondary outcomes

  1. Muscular Strength

    Time frame: 12 weeks

    Using 1 repetition maximum

Sponsors and collaborators

Lead sponsor

Alexei Wong

Other

Collaborators

  • Tehran University

Registry information

Official study title

Comparison of Whole Eggs vs. Egg Whites Consumption on Regulatory Myokines, Muscular Strength, Hypertrophy, Power and Body Composition.

Important dates

Study start
2018
Primary completion
2019
Study completion
2019
First posted
May 8, 2020
Registry last updated
May 8, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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