Peking University Third Hospital
Beijing, China
Location status: Recruiting
NCT Number: NCT05924178
To explore the effect of preoperative exercise rehabilitation on bone mineral density, tendon bone healing, change of cartilage, and gait feature in patients with anterior cruciate ligament rupture.
Interested in participating?
Request Info18 year–45 year
All sexes
Interventional
Not applicable
Beijing, China
Location status: Recruiting
Anterior Cruciate Ligament (ACL) injury is one of the most common sports injuries. It is a serious knee injury. The fracture of ACL can cause functional instability of knee joint, damage of meniscus and articular cartilage, and even induce knee osteoarthritis and other diseases. It has great influence on knee joint and even lower limb function of patients. Arthroscopic ACL reconstruction has become the first choice in clinical treatment of ACL fracture.
ACL fracture can cause local knee joint osteoporosis, and reconstruction surgery can also affect tendon bone healing, bone canal enlargement, rehabilitation period, gait, articular cartilage degradation, etc.
This study intends to conduct preoperative rehabilitation intervention for young people with anterior fork rupture, and explore the effects of exercise rehabilitation on knee bone mineral density, muscle strength, proprioceptive ability and other aspects after ACL rupture, as well as the effects of knee bone mineral density, tendon bone healing, bone tunnel aperture, motor function, gait characteristics and cartilage degradation after reconstruction.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Preoperative exercise rehabilitation in experimental group was performed.
The control group receives conventional treatment preoperative.
Time frame: At 6 monthes post operation.
tendon bone healing by knee MRI
Time frame: At 1 year post operation.
tendon bone healing by knee MRI
Time frame: At preoperative.
Y balance test
Time frame: At 6 monthes post operation.
Y balance test
Time frame: At 1 year post operation.
Y balance test
Time frame: At 6 months post operation.
knee T1 rho value by functional MRI
Time frame: At 1 year post operation.
knee T1 rho value by functional MRI
Time frame: At 6 months post operation.
knee T2 rho value by functional MRI
Time frame: At 1 year post operation.
knee T2 rho value by functional MRI
Time frame: At 6 months post operation.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping
Time frame: At 1 year post operation.
Three-dimensional gait analysis system and plantar pressure were used during walking, running, cutting and jumping
Time frame: At 6 monthes post operation.
tendon bone healing by knee MRI
Time frame: At 1 year post operation.
tendon bone healing by knee MRI
Time frame: At preoperative.
bone mineral density by knee DEX
Time frame: At 6 monthes post operation.
bone mineral density by knee DEX
Time frame: At 1 year post operation.
bone mineral density by knee DEX
Time frame: At preoperative.
Knee isokinetic strength test
Time frame: At 6 monthes post operation.
Knee isokinetic strength test
Time frame: At 1 year post operation.
Knee isokinetic strength test
Time frame: At 2 years post operation.
tendon bone healing by knee MRI
Time frame: At 2 years post operation.
Y balance test
Time frame: At 2 years post operation.
tendon bone healing by knee MRI
Time frame: At 2 years post operation.
Knee isokinetic strength test
Time frame: at pre-operation
CT test
Time frame: At 2 years post operation.
the circumference of 15 cm above the superior aspect of the patella
Time frame: At 1 year post operation.
the circumference of 15 cm above the superior aspect of the patella
Time frame: At 6 monthes post operation.
the circumference of 15 cm above the superior aspect of the patella
Time frame: At pre-operation.
the circumference of 15 cm above the superior aspect of the patella
Time frame: At 1 year post operation.
a maximal-distance hop
Time frame: At 2 years post operation.
a maximal-distance hop
Contact information is provided by the study sponsor or research team.
Peking University Third Hospital
Other
A Study on the Effect of Exercise Rehabilitation on Bone Mineral Density, Reconstruction Ligament Tendon Bone Healing and Cartilage After ACL Rupture and Patellar Dislocation
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
Published trials that share one or more normalized conditions with this study.
NCT07671729
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Injury
Istanbul, Besiktas, Turkey (Türkiye)
View Trial DetailsNCT06956339
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Melbourne, Victoria, Australia
View Trial DetailsNCT05323474
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Challes-les-Eaux, France
View Trial DetailsNCT06511232
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture
Houston, Texas, United States
View Trial Details