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Completed

NCT Number: NCT05949034

Effects of E-Cigarettes in Menthol Smokers

The current laboratory study examines e-cigarette preferences and smoking behaviors in menthol cigarette smokers.

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Key information

Conditions

E-cigarette Use Behavior Smoking Smoking Behaviors Vaping

Age range

21 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Southern California

Los Angeles, California, 90033, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Daily cigarette smoking for at least the past 2 years
  • Interest in trying e-cigarettes
  • Report smoking mentholated cigarettes

Exclusion criteria

-- Pregnancy and/or breastfeeding

Treatment and study plan

JUUL E-Cigarette Device

Device

We will use the commercially available and popular JUUL e-cigarette device and e-cigarette solutions.

Primary outcomes

  1. Preference Ratings

    Time frame: 1 hour

    Self-report measures of product preference will be completed following the e-cigarette self-administration. Scores can range from 0 to 100 for the preference rating, with lower scores representing less preference and higher scores representing higher preference.

  2. Mood - Positive Affect Negative Affect Schedule

    Time frame: 4 hours

    This measure is obtained through the completion of the Positive Affect Negative Affect Schedule. A total score will be calculated for both Positive and Negative Affect. Scores can range from 10 to 50 for both the Positive and Negative Affect, with the lower scores representing lower levels of Positive/Negative Affect and higher scores representing higher levels of Positive/Negative Affect.

  3. Mood - Profile of Mood States

    Time frame: 4 hours

    This measure is obtained through the completion of the Profile of Mood States. A total score will be calculated. Scores can range from 10 to 260, with the lower scores representing lower levels of mood disturbance and higher scores representing higher levels of mood disturbance.

  4. Cigarette Craving

    Time frame: 4 hours

    This measure is obtained through the completion of the Brief Questionnaire of Smoking Urges. A total score will be calculated. Scores can range from 10 to 70, with the lower scores representing a lower level of cigarette craving and higher scores representing greater levels of cigarette craving.

  5. Nicotine Withdrawal - Minnesota Nicotine Withdrawal Scale

    Time frame: 4 hours

    This measure is obtained through the completion of the Minnesota Nicotine Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 32, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.

  6. Nicotine Withdrawal - Wisconsin Smoking Withdrawal Scale

    Time frame: 4 hours

    This measure is obtained through the completion of the Wisconsin Smoking Withdrawal Scale. A total score will be calculated. Scores can range from 0 to 112, with the lower scores representing a lower level of nicotine withdrawal and higher scores representing greater levels of nicotine withdrawal.

  7. Smoking Motivation

    Time frame: 2 hours after experimental session outset

    This measure is obtained through the completion of a computerized behavioral task.

Sponsors and collaborators

Lead sponsor

University of Southern California

Other

Registry information

Important dates

Study start
2019
Primary completion
2020
Study completion
2020
First posted
Jul 17, 2023
Registry last updated
Jul 20, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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