Evaluation of the Be Vape Free Curriculum of the Tobacco Prevention Toolkit

The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students. A set of lessons focused on e-cigarette/vaping prevention education specifically is called the Be Vape Free curriculum. The aims of this study are to determine: (1) whether the Be Vape Free curriculum is effective in increasing middle and high school students' resistance to using tobacco and in decreasing positive attitudes towards and intentions to use e-cigarettes; (2) whether the Curriculum is effective in changing middle and high school students' actual use of tobacco; and (3) Examine heterogenous treatment effects identifying groups that benefit the most and those who do not benefit at all from the intervention.

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Key information

Conditions

E-cigarette Use Behavior Smoking Vaping

Age range

10 year–20 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Stanford University

Palo Alto, California, 94304, United States

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Middle school and high school students receiving health education at schools participating in the study

Exclusion criteria

None

Treatment and study plan

Stanford Vaping Prevention curriculum

Behavioral

Stanford vaping prevention curriculum delivered as a 5-session course administered in a school classroom setting.

Primary outcomes

Change in e-cigarette use

Time frame: Change from baseline to follow-up at approximately 156 weeks

Investigator-originated survey measures (questions) assess ever e-cigarette use & past 30-day tobacco use. This outcome measure assesses e-cigarette use.
Change in intention to use of e-cigarettes scaled score as measured by investigator-originated survey

Time frame: Change from baseline to follow-up at approximately 156 weeks

This survey measures change in intention to use e-cigarettes with questions related to the participant's knowledge of and resistance to use of e-cigarettes.

Sponsors and collaborators

Lead sponsor

Stanford University

Other

Collaborators

National Cancer Institute (NCI)

Registry information

Important dates

Study start: 2022
Primary completion: 2026
Study completion: 2026
First posted: Aug 9, 2022
Registry last updated: May 27, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed