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Completed

NCT Number: NCT01877733

Effective Rehabilitation of Patients Operated With Total Knee Arthroplasty

The purpose of this study is to investigate the effect of maximal strength training (MST) compared to standard rehabilitation in patients operated with total knee arthroplasty. Previous studies report reduced physical function and muscle strength despite successful surgery inserting an artificial implant.

Furthermore, great loss of muscle strength has been found in these patients in the early postoperative phase.

The study is a randomized controlled trial. The investigators hypothesize that MST will increase muscle strength and physical function more than standard rehabilitation.

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Key information

Conditions

Osteoarthritis Arthritis Joint Diseases Musculoskeletal Diseases Rheumatic Diseases

Age range

18 year–75 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

St. Olavs hospital

Trondheim, 7006, Norway

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • unilateral osteoarthritis,
  • < 75 years

Exclusion criteria

  • disease(s) that compromise testing/training,
  • unable to understand written and verbal instructions and information,
  • osteoarthritis in the contralateral leg that needs treatment.

Treatment and study plan

Maximal Strength Training

Other

Primary outcomes

  1. Muscle strength in leg extension and leg press

    Time frame: Measured preoperatively, after 7 days, 10 wks and 1 year

    Measured preoperatively implies measuring the outcome within the last month prior to surgery

Secondary outcomes

  1. 6 minute walk test

    Time frame: preopertively, 7 days postoperatively and after 1 year

    Measuring the outcome preoperatively implies testing within the last month prior to surgery

  2. KOOS; Knee injury and osteosarthritis outcome score

    Time frame: Preoperatively (within 1 month prior to surgery), 7 days postoperatively and 10 wks and 1 year postoperatively

  3. EQ-5D (measure of health outcome)

    Time frame: Preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively

  4. VAS scale recording pain

    Time frame: preoperatively (within 1 month prior to surgery), 7 days, 10 wks and 1 year postoperatively

Sponsors and collaborators

Lead sponsor

Norwegian University of Science and Technology

Other

Collaborators

  • Helse Nord-Trøndelag HF
  • St. Olavs Hospital

Registry information

Important dates

Study start
2013
Primary completion
2015
Study completion
2015
First posted
Jun 14, 2013
Registry last updated
Apr 22, 2020

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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