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NCT Number: NCT06608394

Effect of Preoperative Exercise Habits on Knee Function and Recurrence Rate After Anterior Cruciate Ligament Reconstruction

The aim of this study is to compare the knee function between patients with and without preoperative exercise habits at 1, 2 and 5 years after ACL surgery, and further analyze the effect of maintaining exercise habits on knee function and recurrence rate

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Peking university third hospital

Beijing, Beijing Municipality, 100191, China

Location status: Recruiting

Location contact

CONTACT

10822670720

About this study

Objective:

  • To compare the knee function between active and inactive patients at 1, 2, and 5 years after ACL surgery.
  • To investigate the difference of knee function and recurrence rate between patients with and without postoperative exercise habit.

Methods: This is a single-center, controlled follow-up cohort study. Inclusion criteria included patients aged 18-45 years with confirmed ACL injury who were scheduled to undergo ACL reconstruction surgery. Exercise habits were recorded before operation, and knee joint function and exercise level were evaluated by questionnaires. All patients received standardized ACL reconstruction surgery and rehabilitation program after surgery. In prospective cohort study, 121 patients were divided into running group and non-running group according to their preoperative exercise habits. At 3 months after surgery, running was included in the rehabilitation program, and the patients were further divided into postoperative running and non-running groups and followed up for one year.In Postoperative cohort study, follow-up was collected and evaluated at 1 year, 2 years and 5 years, including knee function, exercise level and recurrence. The study was divided into four groups: preoperative running group , preoperative non-running group , preoperative and postoperative running group and preoperative non-running and postoperative running group to analyze the effects of preoperative and postoperative exercise habits on knee joint function and recurrence rate. The results of this study will help to deepen the understanding of the impact of preoperative exercise habits and postoperative exercise maintenance on knee function and recurrence rate after ACL reconstruction, and then provide guidance for clinical practice, optimize postoperative rehabilitation programs, and ultimately improve the quality of life of patients.

Subjects: Patients with anterior cruciate ligament rupture in Department of Sports Medicine, Peking University Third Hospital 1.1.1 Inclusion criteria

  • Age of 18-45 years old, male or female.
  • Patients were diagnosed with anterior cruciate ligament injury and planned to undergo anterior cruciate ligament reconstruction surgery 1.1.2 Exclusion criteria Presence of other severe knee disorders (e.g., arthritis).
  • Prior history of other knee surgeries
  • Inability to complete a postoperative rehabilitation program or long-term follow-up.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with anterior cruciate ligament rupture in Department of Sports Medicine, Peking University Third Hospital

Exclusion criteria

  • Severe other knee disorders (e.g., arthritis) are present.
  • Prior history of other knee surgeries
  • Inability to complete a postoperative rehabilitation program or long-term follow-up

Treatment and study plan

No intervention

Other

no intervention

Primary outcomes

  1. Lysholm knee score

    Time frame: 1year,2year,5year

  2. IKDC score

    Time frame: 1year,2year,5year

  3. Tegner score

    Time frame: 1year,2year,5year

  4. Beighton Score

    Time frame: 1year,2year,5year

Secondary outcomes

  1. recurrence rate

    Time frame: 1year,2year,5year

Study contacts

Contact information is provided by the study sponsor or research team.

Jianquan wang

CONTACT

[email protected]

13801076267

Ruiqin dang

CONTACT

[email protected]

19261022008

Sponsors and collaborators

Lead sponsor

Peking University Third Hospital

Other

Registry information

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 23, 2024
Registry last updated
Feb 12, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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